Renal Protective Efficacy of Terminalia chebula, Terminalia bellirica, Phyllanthus emblica and their Formulation as Triphala on Imidacloprid Induced Renal Toxicity by Histopathological and Biochemical Parameters
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 5
Abstract
Effect of Imidacloprid induced renal damage and its amelioration was carried out at definite time periods in different groups for 28days and experimented. Biochemically evaluated with renal markers it showed elevated level of urea, uric acid, creatinine, sodium and decreased in potassium the mineral element. Administration of Imidacloprid produced, renal tubules congestion, mild vacuolar degeneration, edema in Bowman’s capsule (40mg/kg/b.w), disintegration of Bowman’s capsule, dilation of capillary tubules, renal tubule congestion, vacuolar degenerations were observed in (80mg/kg/b.w). Animals were treated with Terminalia chebula, Terminalia bellirica, Phyllanthus emblica and their formulation called Triphala (1:1:1) drug. Phyllanthus emblica has shown extraordinary effect of renal protective role comparing the four samples which was proved virtually.
Authors and Affiliations
*Dr. V. Eugin Amala, Dr. M . Jeyaraj, M. Meldintha Mary3
Keywords
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- EP ID EP391148
- DOI 10.9790/3008-1205036974
- Views 63
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