Resealed erythrocytes a specified tool in novel drug delivery system
Journal Title: International Journal of Pharmaceutical and Medicinal Reserach - Year 2017, Vol 5, Issue 1
Abstract
Among the various carriers used for targeting drugs to various body tissues, the cellular carriers meet several criteria desirable in clinical applications, among the most important being biocompatibility of carrier and its degradation products. Leucocytes, platelets, erythrocytes, Nano erythrocytes, hepatocytes, and fibroblasts etc have been proposed as cellular carrier systems. Among these, the Resealed Erythrocytes have been the most investigated and have found to possess greater potential in drug delivery. The main objective of this review is to explore the various features, drug loading technology, and biomedical applications of resealed erythrocytes. It deals with the various research work done on Resealed Erythrocytes providing an overall review about the different advantages and applications of Resealed Erythrocytes in different fields. Wide varieties of drugs like Anti- inflammatory, Steroidal and Chemotherapeutic agents are seen to have reduced side effects upon incorporation into these carriers. The morphology, isolation techniques, properties and methods of drug loading are highlighted in this paper along with the characterization and applications of resealed erythrocytes.
Authors and Affiliations
Vaishali Goel, Charanjeet Kaur, Rainu Devi, Aman Kumar, Ujjwal Nautiyal
Keywords
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