Research progress of dendritic cells and atherosclerosis
Journal Title: Journal of Air Force Medical University - Year 2023, Vol 44, Issue 8
Abstract
Atherosclerosis (AS) is an important factor leading to cardiovascular and cerebrovascular events. Early detection and intervention are the most economical and effective means to improve the survival prognosis of patients. However, the pathogenesis of AS has not been fully elucidated. Previous studies on AS have focused on the formation of monocyte-macrophage-foam cells and the injury of endothelial cells, and in recent years, it has been found that dendritic cell (DC) can also be involved. DC is an important innate immune cell that can effectively initiate adaptive immune response, which involves complex processes such as cytokine secretion and intracellular signal transduction. It is of great significance to further understand the relationship between DC and AS.
Authors and Affiliations
WANG Zihuan, SHI Xiangui, LYU Jianjun, WANG Ting, JIANG Jianli, NAN Gang
Keywords
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