Research progress of psychological and biological mechanism of childhood trauma affecting social anxiety disorder
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 9
Abstract
Social anxiety disorder has a significant negative impact on individuals’ social interaction and normal life, and childhood trauma plays an important role in the occurrence and development of SAD. Childhood trauma affects the development of self-awareness, impairs the ability of information processing, hinders the normal development of prefrontal cortex-limbic system loop and default mode network, and causes abnormal secretion of glucocorticoid and oxytocin, which leads to individuals’ inability to correctly understand social clues and reasonably regulate emotions, and thus unable to produce adaptive emotional and behavioral responses in social situations, which may lead to SAD. In conclusion, childhood trauma has a lasting adverse effect on social function from both psychological and physiological aspects.
Authors and Affiliations
Yitong LIU, Shuya YAN, Jingyan SUN, Shuming ZHONG, Yanbin. JIA
An intervention study of right unilateral modified electroconvulsive therapy for major depressive disorder
ObjectiveTo explore the effect and safety of right unilateral modified electroconvulsive therapy (RUL-MECT) for major depressive disorder patients (MDD).MethodsA randomized controlled trial was conducted on 70 patients w...
The clinical value of visual evoked potential in assessing visual pathway of visual hallucinations in Parkinson disease
[Objective] This research was to evaluate the integrity of visual pathways in patients with Parkinson disease (PD) by visual evoked potential (VEP), especially those with visual hallucinations. [Methods] A total of 76 PD...
A progress in neuroimaging research on the central mechanisms of botulinum toxin in the treatment of focal dystonia
Botulinum toxin (BoNT) is currently the first-line method for treating focal dystonia, which causes muscle paralysis by chemical denervation. Recent neuroimaging studies have found that BoNT treatment could alter neuropl...
A case report of COVID-19-associated acute necrotizing encephalopathy
This article reports one case of adult COVID-19-associated acute necrotizing encephalopathy (ANEC) .The patient developed disturbance of consciousness and seizure on the 12th day after SARS-CoV-2 infection. Imaging showe...
Risk factors for suicidal ideation among relatives and friends of suicide victims on psychological support hotline
[Objective] To explore the risk factors for suicidal ideation among the relatives and friends of suicide victims through psychological support hotline. [Methods] Calls from the relatives and friends of suicide victims to...