Research progress on multiple mechanisms underlying visual hallucinations in schizophrenia patients
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 8
Abstract
Visual hallucination (VH) is a common symptom of schizophrenia, the underlying mechanism has not been fully elucidated. It has been found that the dysfunction of dopamine (DA) system, the overactivation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate (AMPA) receptor in glutamate system and the dysfunction of γ-aminobutyric acid (GABA) ergic neurons can induce VH in patients with schizophrenia. In addition, abnormalities in brain structural and functional networks and visual networks are also closely related to the occurrence of VH. The purpose of this paper is to review the neurochemistry and nerve injury mechanism of VH in schizophrenic patients to deeply understand the characteristics of VH, and make more accurate judgment in the early diagnosis, condition evaluation and treatment plan of schizophrenic patients.
Authors and Affiliations
Yuchen JIANG, Qiongyi HAN, Xiaocui DU, Guoting ZHEN, Jindong TIAN, Yao GAO, Sha LIU, Xinzhe DU
Keywords
Related Articles
- EP ID EP750535
- DOI 10.3969/j.issn.1002-0152.2024.08.010
- Views 59
- Downloads 0
The effect evaluation of revision operation for cubital tunnel syndrome followed surgical treatment
[Objective] To explore the causes of postoperative revision for cubital tunnel syndrome(CTS),summarize the details of revision surgery for CTS and evaluate the efficacy,in order to reduce the revision probability of the...
A case of propriospinal myoclonus with typical axial convulsions during sleep
Propriospinal myoclonus (PSM) is a rare painless movement disorder characterized by recurrent axial myoclonus during the wake and sleep transition periods. The recurrent muscle twitches during the hypnotic period severel...
The application of fuorescein sodium for the microscopic resection of medulloblastoma
[Objective] To investigate the safety and efficacy of sodium fluorescein-guided microsurgery in children with medulloblastoma, and to analyze the surgical efficacy and prognosis.Among them, 12 cases underwent unilateral...
The clinical value of visual evoked potential in assessing visual pathway of visual hallucinations in Parkinson disease
[Objective] This research was to evaluate the integrity of visual pathways in patients with Parkinson disease (PD) by visual evoked potential (VEP), especially those with visual hallucinations. [Methods] A total of 76 PD...
Comparison of abnormal cortical inhibition in schizophrenia and major depression disorder
[Objective] To compare cortical inhibition (CI) function between patients with schizophrenia and depression, and to explore the correlation between CI function and clinical symptoms. [Methods] A total of 35 first episode...