Resistance to beta-lactamines of several pathogenic germs
Journal Title: Terapeutica, Farmacologie si Toxicologie Clinica - Year 2008, Vol 12, Issue 3
Abstract
[b]Premises [/b]The antibiogram is one of the most frequent determination from a bacteriology laboratory being required on multiple clinical, epidemiological and research considerations. Scientifically, antibiogram is made for the research of the resistance phenomenon through which the bacterias with etiological role in human infections are or become resistant to antibiotics. [b]Objectives [/b]The object of the study is to estimate the resistance of the several pathogenic germs (Klebsiella, Escherichia coli, Proteus, Staphylococcus aureus) isolated from various pathological products, to several beta-lactamic antibiotics usually used in medical practice: Imipenem+Cilastatin, Ampicillin+Sulbactam, Ampicillin+Acid clavulanic, Cefotaxim, Ceftazidim, Ampicillin. [b]Material and method [/b]In our study, there were used bacterian cultures isolated from pathological products from a lot of 37 adult patients, most of them with urogenital pathology and acute or chronic respiratory infections affections. The sensibility and resistance of the pathogenical germs reminded before using difusimetrical antibiogram. Results and conclusions E. coli became resistant to Imipenem+Cilastatin, the sensibility of Klebsiella and Proteus was not modified, while the sensibility of the Staphylococcus dropped, although the Staphylococcus remained receptive to this antibiotic. E. coli kept it’s sensibility towards Ampicillin+Acid clavulanic action unlike the other studied germs where a tendency to became resistant was observed. The Ampicillin+Sulbactam only E. coli and Proteus have an intermediate sensibility. The Staphylococcus is the one who responds best to Cefotaxim therapy, followed by Proteus. In the case of Klebsiella, one can, one can see the tendency to become resistant to this antibiotic, while in the case of the E. coli the definitive resistance to Cefotaxim is observed. None of the germs are sensible anymore to Ceftazidim. Towards Ampicillin it is observed the tendency to become resistant, only the Staphylococcus and Proteus have an intermediate sensibility.
Authors and Affiliations
Carmen Avramescu, Maria Bălăşoiu, Adriana Turculeanu, Anca Ungureanu, Isabela Siloşi, Simona Neamţu, Oana Ionete, Mădălina Sibişeanu
Keywords
Related Articles
- EP ID EP84333
- DOI -
- Views 103
- Downloads 0
Calcium needs in childhood. Clinical and therapeutic aspects
Childhood is defined as a dynamic growth process with a variable rate depending on age. Estimations state that osseous mass grows 7 times from birth to puberty. The calcium needs for human body varies significantly throu...
Clinicals, epidemiologicals and therapeutics features of patients with Acute Limphoblastic Leukemia in Hematology Clinic-Timişoara
Acute limphoblastic leukemia is a clonal neoplazic profileration of the progenitor limphoids stem cells characterized by their differentation stop and growth, the incidence of the disease being influenced by age, sex, et...
Prognostic score of hyperlactatemia under ART
Background: mitochondrial toxicity is an adverse event of nucleoside reverstranscriptase inhibitors. The biochemical marker is the increased level of serum lactate. Objectives: to identify the risk factors for hyperlacta...
Resistance to beta-lactamines of several pathogenic germs
[b]Premises [/b]The antibiogram is one of the most frequent determination from a bacteriology laboratory being required on multiple clinical, epidemiological and research considerations. Scientifically, antibiogram is ma...
The oxidative stress impact on the brain aging
The brain aging is a complex process with anatomical, chemical and functional impact. The structural changes are not homogenonous and are related with engenous and exogenous factors. Brain aging is influenced by the ox...