Respiratory Syncytial Virus Infection among Children in Lagos, Nigeria
Journal Title: Journal of Clinical Immunology & Microbiology - Year 2021, Vol 2, Issue 1
Abstract
Background Information: Acute Lower Respiratory Tract Infections (ALRTIs) are among the major cause of mortality and morbidity worldwide. Respiratory Syncytial Virus (RSV) is recognized as the most important viral cause of ALRTIs in children under the age of five years. Objectives: This study determined molecular prevalence of RSV among under five children admitted with ALRTTIs in a tertiary hospital, Lagos State University Teaching Hospital (LASUTH), Ikeja, Lagos State. It also highlighted the clinical presentation and identifies the risk factors associated with the acquisition of RSV-ALRTIs. Methods and Materials: A hospital based cross-sectional study conducted among children under the age of five years diagnosed and admitted with ALRTIs in the paediatric department of LASUTH. Nasopharyngeal swabs were obtained from the participants for the determination of RSV using Reverse Transcriptase Polymerase Chain Reaction (RT-PCR). Data was analyzed by both descriptive and inferential statistics using SPSS. Results: A total of 200 participants were recruited over a period of eight month. Forty five (22.5%) had detectable RSVRNA. The prevalence of RSV was highest among the age group 2-6 month (32.4%). The main clinical symptoms of RSV-ALRTIs were fever, cough, tacypnoea and chest wall in drawing. Conclusion: This study showed that RSV is an important viral cause of ALRTIs necessitating hospitalization in children under the age of five and the imperative for rapid, easy and less expensive method of diagnosis of RSV infection to avoid unjustifiable use of antibiotic.
Authors and Affiliations
Oluwadamilare Afolabi Obe, Bamidele Wasiu Mutiu, Abimbola Amoo*
Keywords
Related Articles
- EP ID EP699093
- DOI http://dx.doi.org/10.46889/JCIM.2021.2107
- Views 99
- Downloads 1
Lyme Disease-An Emerging Metazoonosis of Public Health Concern
Recent decades witnessed the emergence of several zoonotic diseases, such as bird flu, Ebola disease, Nipah virus disease, severe acute respiratory syndrome, swine flu, COVID-19 and others [1]. The emergence of these z...
Scanning Ion Microscopy and Its Application in Microbiology
Helium ion microscopy, a scanning microscope operating with ions rather than electrons, is one of the best equipment to analyze the surface of cells and the surface of intracellular compartments exposed by different meth...
Cooling the Lower Abdomen for Pain Relief, Boosting the Immune System, Stopping the Hot Fleshes During Menopause and Better Sleep
The article is about cooling (with cold water) of the lower abdomen (which is most sensitive to cold) for: relief of abdominal pain, boosting the immune system, handling hot flashes during menopause and better sleep. The...
COVID-19 Infections and Vitamin D Deficiency in Pregnancy
Corona virus disease COVID-19 has been a global health threat since November 2019. It has been reported as 6th cause of global public health emergency by World Health Organisation on January 2020. Serum cholecalciferol...
Evaluation of Antibiotic Resistance in Pediatric Patients Suffering from Cancer
Introduction: The discovery of antibiotics has revolutionized the field of healthcare since many lethal infections which were previously impossible to treat are now have become much curable. However, a high reliance of t...