RETROSPECTIVE ANALYTICAL STUDY OF ASSOCIATION BETWEEN ABO BLOOD GROUP AND MALIGNANCY
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 55
Abstract
BACKGROUND The findings of Arid et al in 1953 regarding association between carcinoma of stomach and B blood group and successively in 1954 regarding association between peptic ulcer and O blood group opened a new approach to find association of blood group with other commonly occurring diseases. Blood type antigen system maybe apparently involved in the pathophysiology of wide range of human malignancy by interaction between glycan structures on red blood cells surface and different agents. Therefore, the present study aims to find out to examine the association between ABO blood group and different forms of malignancy, so that a preventive measure can be applied to the risk blood group population. MATERIALS AND METHODS Thirty (30) diagnosed malignant cases as study group and thirty (30) non-malignant cases as control group were selected amongst the surgical patients and ABO blood group were collected and registered. The ABO blood group and Rh factor of both the groups were determined using the tile or slide testing method and the frequency of occurrence of ABO and Rh blood group among malignant and non-malignant population was assessed. The frequency distribution of ABO blood group and Rh factor among the entire malignant population was compared with that of general non-malignant population by Chi-square test. RESULTS The present study indicates that the blood group (B) appears to have higher risk of developing malignancy compared to people of other blood groups, but it is insignificant as per Chi-square test. CONCLUSION The present study suggests that ABO blood group was found to be of non-potential risk factor in the development of malignancy
Authors and Affiliations
Siladri Sengupta, Subhadip Sarkar, Adnan Rehan Khan
Keywords
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- EP ID EP225893
- DOI 10.14260/Jemds/2017/897
- Views 90
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