Retrospective Study of Who Grade of Urothelial Carcinoma and Its Immunohistochemical Correlation with P53 and P63.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2019, Vol 4, Issue 4
Abstract
Background: Tumors of the urinary bladder contribute significantly to the human cancer burden. Cancer of the urinary bladder accounts for about 3.2% of all cancer worldwide, with an estimated 260,000 new cases occurring each year in men and 76,000 in women. Methods: Hospital record based retrospective study conducted in the Department of Pathology, Dr. S. N. Medical College, Jodhpur. The duration of study was from January 2016 to January 2018 . Results: A statistically significant correlation was observed between the histopathological stage and p53 immunoexpression&p63 immunoexpression. Conclusion: Urothelial carcinoma is potentially life threatening and expensive to treat, since for many patients , the diagnosis entails a lifetime of surveillance to detect recurrent disease. Early identification of patients , whose superficial tumors will progress or recur , is very important , because changes in their treatment strategies can have a major impact on the outcome of the disease.
Authors and Affiliations
S. R. Negi
Keywords
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