Review on data analysis and application of high-throughput peptide arrays
Journal Title: Shanghai Journal of Preventive Medicine - Year 2023, Vol 35, Issue 1
Abstract
This article introduces a high-throughput molecular screening chipï¼ peptide arrays. As a kind of biochipï¼ the peptide arrays are easy to synthesisï¼ stable in probe chemistryï¼ high-throughput in screening and highly specific compared with other biochips. To analyze the new high-throughput dataï¼ researchers have recently proposed a series of deep learning and bioinformatics methods to study the binding characteristics of peptide probes and target molecules. Those algorithms could be used to predict the binding affinity of protein targets against peptides. Moreoverï¼ peptide arrays could also play important roles in analyzing protein-protein interactionsï¼screening novel drug peptidesï¼ disease diagnosis and general health assessment based on recent reports. The application of this new technology could provide novel insights into public health research.
Authors and Affiliations
HUANG Junxiong,TAO Yimin,ZHONG Pei,ZHAO Chunqing,LI Xiaoguang,WANG Hui,
Keywords
Related Articles
- EP ID EP742069
- DOI -
- Views 21
- Downloads 0
Comparative analysis of disease burden in Sichuan Province in 2010 and 2020 based on disability-adjusted life years
ObjectiveTo analyze the disease burden in Sichuan Province in 2010 and 2020ï¼ and to provide reference for disease prevention and control.MethodsMonitoring data on causes of death in Sichuan Province in 2010 and 2020 we...
Population and chigger mite infection of rodents in Pudong New Areaï¼ Shanghai
ObjectiveTo investigate the population and chigger mite infection of rodents in Pudong Districtï¼ Shanghaiï¼ so as to provide the scientific basis for the prevention and control of rodents and chigger transmitted disea...
Mycoplasma pneumoniae infection and macrolide resistance of children hospitalized in Ningbo Areaï¼ Zhejiang Province in 2019â2021
ObjectiveTo investigate Mycoplasma pneumoniae ï¼MPï¼ infection and macrolide resistance of hospitalized children in Ningbo Area in 2019â2021.MethodsA total of 6 782 respiratory throat swab specimens were collected fr...
Research on the establishment of capability evaluation system and training and exercise models of the national emergency medical rescue team
Objective To improve the response capabilities to disasters and prevent major epidemics， it is of practical use to study the capability evaluation system of the national emergency medical rescue team that combines theor...
Current status of book publishing in the field of biological weapons defense in China
Objective To provide scientific support for the compilation of high-quality anti-nuclear， biological， and chemical （NBC） medical textbooks in China by retrieving books in the field of biological weapons defense in Ch...