Review on effect of combination drug therapy on diabetes mellitus and its management
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2014, Vol 2, Issue 1
Abstract
Diabetes is a chronic condition associated with abnormally high levels of sugar (glucose) in the blood. Insulin produced by the pancreas lowers blood glucose. Absence or insufficient production of insulin causes diabetes. An inactive life, which involves lack of exercise and poor calorie management, is one of the biggest contributors to the dreaded disease of diabetes, today. India is facing an epidemic of diabetes. At present, confirmed diabetes patients in India are 67 million, with another 30 million in prediabetes group. By 2030, India will have the largest number of patients in the world. Diabetes is not only a blood sugar problem, but brings along other complications as well. With a person dying and two cases being identified every ten seconds, diabetes is certainly one of the biggest global challenges. And as per WHO report 2012 if India doesn’t awake from its slumber, by 2025, every fifth diabetic on earth would be an Indian. At present there are around 171 million diabetic people all over the world, and India accounts for more than 40 million who are likely to reach 70 million by 2025. Diabetes doesn’t even spare the young Indians as 11.1 % adult males and 10.8 % adult females are suffering from it. Diabetes eventually result sin many fatal diseases such as stroke and heart attack, and, as per WHO estimates, mortality from diabetes including heart disease, kidney failure and others cost India $210 billion in 2005. It would cost India $ 333.6 billion over the decade.
Authors and Affiliations
Sovindra Kumar Bharti, Avantika Srivastava, Ranjeet Singh
Formulation and in-vitro evaluation of extended release matrix tablets of Mefenamic acid
Extended release formulations make the drug available over extended time period after oral administration. The Extended release will optimize therapeutic effect and safety of a drug at the same time improving the patie...
Spectrophotometric Determination of Capacetabine via their Metal Chelate
A simple, sensitive and accurate spectrophotometric method was described for the estimation of Capacetabine(CPB) a prodrug used as a chemotherapeutic agent used to treat of cancer either in pure form or in the tablet.T...
REVIEW ARTICLE ON ANTIMICROBIAL RESISTANCE
Antimicrobial resistance (AMR) is not a recent phenomenon, but it is a critical health issue today. Over several decades, to varying degrees, bacteria causing common infections have developed resistance to each new ant...
EFFECTIVE HYPOGLYCEMIC ACTION OF METFORMIN COMBINATIONS AGAINST DEXAMETHASONE INDUCED DIABETES MELLITUS IN RATS
Diabetes mellitus is a chronic metabolic disorder occurs due to the damage of β-cells of islets of Langerhans in pancreas. In general patients suffering for diabetes mellitus always use the medicines, apart from the me...
A new method development and validation for the simultaneous estimation of Zolpidium and Melatonin by using RP HPLC in a bulk and pharmaceutical dosage forms
A simple and selective Liquid Chromatography method was described for the determination of Melatonin and Zolpidem tartarate in tablet dosage forms. Chromatographic separation was achieved on a c18 column using mobile p...