Rheumatoid arthritis and herbal drugs: A review
Journal Title: The Journal of Phytopharmacology - Year 2015, Vol 4, Issue 6
Abstract
Rheumatoid Arthritis (RA) is a chronic autoimmune disease of unknown aetiology that affects 0.5% of the population and can result in disability owing to joint destruction, characterized by joint synovial inflammation and progressive cartilage and bone destruction resulting in gradual immobility. The greatest disadvantage in the presently available potent synthetic drugs lies in their toxicity and reappearance of symptoms after discontinuation. With limitations of existing drug molecules herbal drugs are gaining interest among RA patients. Medicinal plants are plants containing inherent active ingredients used to cure disease or relieve symptoms of arthritis. The aim of this review is to update information on RA including causes, epidemiology, prevalence, symptoms and diagnosis, classification, medications, toxicities of allopathic anti-rheumatic drugs and importance of herbal drugs for the management of RA. The present review also focuses on the medicinal plants that interact with the mediators of inflammation and are used in the treatment of rheumatoid arthritis (RA).
Authors and Affiliations
Jyoti B. Wadekar, Ramesh L. Sawant, Unnati B. Patel
Pharmacognostic, phytochemical, physicochemical and TLC profile study Mace (Aril) of Myristica malabarica Lamk. (Myristicaceae)
The plant Myristica malabarica Lamk. is traditionally used as a medicine and spices in food . It is belonging to family Myristicaceae. The plant is native to India and endangered trees are mostly found in western ghat....
Effect of Centella asiatica against anti-tuberculosis drugs-induced hepatotoxicity: Involvement of mitochondria and oxidative stress
The liver is an integral organ in the body and plays a vital role for the metabolism of endogenous and exogenous agents. Drug-induced liver toxicity is one of most common cause of liver injury. It accounts for approxim...
Antiinflammatory and antioxidant activity of extracts and isolated compounds from Derris brevipes Benth (Baker)
The role of medicinal plants in promoting the ability of human health to cope with the unpleasant and difficult situations is well documented from ancient times till date all over the world. The purpose of this study i...
In vitro Antimicrobial Activities of Crude Extracts of Vernonia amygdalina and Croton macrostachyus against Some Bacterial and Fungal Test Pathogens
The aim of the present study was to investigate the antibacterial and antifungal activities of crude extracts of Vernonia amygdalina and Croton macrostachyus against four bacterial pathogenic species (i.e. Staphylococc...
Insulin and alpha amylase levels in alloxan-induced diabetic rats and the effect of Rothmannia hispida (K. Schum) Fagerl leaf extract
Objectives: Rothmannia hispida (R. hispida) is used in West African traditional medicine for the treatment of various ailments such as fever, dysentery, skin infections, abdominal pain and diabetes mellitus. To elucidat...