Rocuronium Use in Neonate: A Review Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 4
Abstract
Neuromuscular blocking agents (NMBAs) are used in a range of critical illnesses in neonates and infants, despite a lack of guidelines and professional standards. This study reviewed the current evidence base and practice regarding the continuous use of these agents in this age range. An online literature search for NMBA (Rocuronium) use in neonates was performed using PubMed, MEDLINE and EMBASE. The search terms used were Rocuronium, neuromuscular block, muscle relaxant and neonate, infant, NICU. In conclusion there are some supportive data regarding short-term efficacy of intermittent NMBA use in neonates, but the long-term effects remain unknown. However, while consensus statements and accepted standards regarding NMBA use and assessment exist in both adult and paediatric intensive care units, there seems to be limited information available to guide those using NMBAs in neonatal intensive care units (NICUs). Considering the possible toxicity and side effects of these drugs, further research into their effects on neonatal physiology is needed.
Authors and Affiliations
Mohammed Abduh Alshafyie
Keywords
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- EP ID EP534117
- DOI 10.21276/ijmrp.2018.4.4.002
- Views 85
- Downloads 0
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