Role of Anti-Oxidant Vitamin C in Post Operative Pain Relief in Foot and Ankle Surgery
Journal Title: Journal of Medical Science And clinical Research - Year 2017, Vol 5, Issue 12
Abstract
Aims and Objectives: The primary objective of the study is to assess the efficacy of Anti-oxidant Vitamin C in postoperative pain relief in foot and ankle surgery. Materials and Methods: This is a Randomized Comparative double blinded study. A minimum of 60 subjects were selected for the study. Study subjects were systematically and randomly allocated into two groups of 30 each (Group A and Group B) receiving either Vitamin C or Placebo depending upon randomization by closed envelope technique. Patients who had foot and ankle surgery received a course of tablets for a period of 6 weeks, starting from first postoperative day. Results: The mean VAS Score at first week in group 1 was 63.33±14.70 and in group 2 was 69.33± 14.33 while at second week the VAS Score in group 1 improved to 20.37 ± 19.11 and in group 2 improved up to 31.03 ± 17.6. The VAS Score at six week in group 1 was 0.67 ± 2.54 and in group 2 was 3.33 ± 8.44. Patients on further follow ups had occasional pain at rest. The functional outcome evaluation using “FOOT AND ANKLE CORE SCORE” at final follow up in group 1 in terms of standardized mean was 72±3.95 and group 2 was 62.45±9.2. The normative score at final follow up in group 1 was 32.79±3.09 and in group 2 was 25.55±6.30. Conclusion: vitamin C is an effective prophylactic agent following trauma to extremities and also after scheduled surgeries to decrease postoperative pain and decrease the need for analgesia and for better functional outcome of the patient for early rehabilitation of the patient.
Authors and Affiliations
Imran Khan
Keywords
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