Role of Antiphospholipid Antibody in Early Pregnancy Loss
Journal Title: International Journal of Pharma Research and Health Sciences - Year 2015, Vol 3, Issue 2
Abstract
Aim & objective- To detect correlation between antiphospholipid antibodies in early pregnancy losses. Material & Method- In this study 70 patients were taken from the department of obstetrics and gynaecology of M.L.B. Medical College , Jhansi in year 2013. Patients were investigated for antiphospholipid antibodies and lupus anticoagulant after complete history, examination and investigation of recurrent pregnancy loss. Patients were divided in two groups. Group -1: Patients having history of 2 or more abortions. (Study group) Group -2: Patients having normal obstetrical history. (Control group) Results- Majority of patients study group were in range of 20-25 year age group. Majority of abortions (68.89%) occurred during 1st trimester. Positive test for antiphospholipid was 6.67% (3 patients) in study group while none was positive in control group (P=<.001%). Majority of positive patients were positive for anticardiolipin antibody. Conclusion- Antiphospholipid antibodies have a definite role in early pregnancy loss.
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