Role of Apparent Diffusion Coeffecient (ADC) Value in the Evaluation of Benign Intradural Extramedullary Spinal Canal Lesions
Journal Title: International Journal of Contemporary Medical Research - Year 2017, Vol 4, Issue 12
Abstract
Introduction: Diffusion weighted sequence is a special type of sequence used in the MR imaging.It is based on the microscopic movement of the water molecules within the cells. Highly cellular lesions show reduced diffusion of the water molecules. ADC value is calculated from the diffusion weighted imaging which measures the diffusion values in all the voxels. The ADC value decreases with reduced diffusion and vice versa.In this study we have evaluated the ADC values of different intradural and extra medullary spinal canal lesions. Study aimed to perform the diffusion weighted imaging and evaluate the apparent diffusion coefficient values of benign intradural extra medullary spinal canal lesions. Material and Methods: The study was performed in the Department of radiology during January 2014 to April 2017 using 1.5T GE and 1.5T Siemens Magnetom Avanto MRI system. The study included 35 patients with intradural extra medullary spinal canal lesions which was confirmed on conventional MRI and for whom subsequently diffusion weighted MRI was performed. The ADC values were calculated and correlated with the Histopathologic examination reports. Results:The mean ADC value of benign intradural extramedullary lesions is 1.62 x10-3mm2 /sec varying between 0.82-2.82 x10-3mm2 /sec. 74% of the lesions were seen in the males. The commonest lesions are Meningiomas, Ependymomas, Nerve sheath tumours and Arachnoid cysts. The Epidermoid cyst has the lowest ADC values whereas the Arachnoid cyst has the highest ADC value. Conclusion:Diffusion Weighted Imaging and Apparent Diffusion Coefficient values aid in the evaluation of benign intradural extramedullary spinal canal lesions.
Authors and Affiliations
Chaithra Nagabhushan, Kumaresh Athiyappan, Sheila Elangovan
Keywords
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