Role of Consanguinity in Mental Retardation
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 7
Abstract
Introduction: Intellectual disability is defined as a disability characterized by significant limitations in both inte llectual functioning and in adaptive behavior. Mental retardation can be caused by a range of environmental an d genetic factors that lead to a combination of cognitive and social impairments. In Indian culture, consanguine ous marriages are more common, may be due to various customs, traditions, beliefs, the desire to preserve famil y property and to maintain relationships etc., In children with mental retardation, role of consanguinity among parents is debatable. Aim: To find the correlation between consanguinity and mental retardation. Methodology: A retrospective study was done at Government Hospital for Mental Care, Visakhapatnam over a period of one year where 421 patients diagnosed with mental retardation as per ICD 10 criteria were included i n the study. Results: Of 421 patients, 274 were males and 147 were females. Among 135 patients in consanguineous group, 38.51% (52), 32.59% (44), 19.25% (26) and 9.6% (13) had mild, moderate, severe and profound MR respectivel y while among 286 patients in non consanguineous group, 51% (146), 28% (80), 12% (35) and 8% (25) had mil d, moderate, severe and profound MR respectively. Statistically no significant relation was observed between co nsanguinity and mental retardation. Conclusion: The causal relation of consanguinity with mental retardation could not be established.
Authors and Affiliations
Dr Radhika Onteddu, Dr Susmitha Gajula, Dr V Padma
Keywords
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