Role of Ranibizumab in various retinal disorders
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 3
Abstract
Purpose: Our aim was to evaluate role of anti VEGF Ranibizumab in diabetic CSME, Wet ARMD and retinal vein occlusion Method: The present study was conducted in 100 patients who presented themselves in OPD of upgraded department of Ophthalmology ,N.S.C.B.Medical college, Jabalpur (M.P.) during the academic session October 2014 – September 2016.All selected patients were given Intravitreal Ranibizumab on monthly basis after full history as well as thorough clinical examinations followed by treat and extend norms.OCT evaluation for central retinal thickness and visual acuity measurement was done prior to, after each injection as well as after completion of therapy. Result: The mean no. of intravitreal Ranibizumab injections over 2 years was 5.6 per patient. Before starting therapy most of the patients had visual acuity of 6/36 on snellens vision chart with average CFT(central foveal thickness )of 563 μm. After 2 years the mean OCT measured CFT improved to 463μm . In most of the patients vision is improved by 15 letters i.e. approximately 3 lines while few patients had stability of vision and very few no. of patients had deterioration of vision. Conclusion: Ranibizumab is associated with clinically and statistically significant benefit with respect to visual acuity and reduction of CFT.
Authors and Affiliations
Dr. Pervez Ahemed Siddiqui, Dr. (Mrs. )Padmini Warkhede
Keywords
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- EP ID EP595954
- DOI 10.9790/0853-160305142147
- Views 52
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