Role of Serum Prolactin Levels in Differentiate Childhood Seizure Episodes and Conditions Mimicking Seizure Episodes
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2017, Vol 16, Issue 12
Abstract
Background: Seizure disorder is the most common neurological problem in children. Acute seizures are a common cause of pediatric admission to hospitals. Objective:This study aimed to determine the role of Serum Prolactin level in different type of Seizures and Seizure like activity in children, and correlate with the post-ictal duration. Many patients being treated as epileptics are not actually so. Moreover the coexistence of pseudoseizure with epilepsy is high.There is no single exposure ,biochemical marker to differentiate between epileptic and non-epileptic seizures. Materials and methods: This study was carried out in the department of Pediatrics and Neonatology, RIMS, Ranchi from March 2015 to September 2016. The present study was done on 75 cases of study group and 25 cases of control. The study group was divided into three groups of 25 cases each : Group I: (Generalised Tonic Clonic Seizures, Complex Partial Seizure, or Simple Partial Seizure).Group II : (Febrile Convulsion).Group III : (conditions mimicking seizures).Blood was collected within 2 hours of seizure and prolactin levels assayed. Results: Prolactin levels were significantly high only within Group I .But in other group prolactin level was within normal limit. Conclusion: The clinical usefulness of post-ictal prolactin estimation is restricted to the positive diagnosis of epileptic seizures.
Authors and Affiliations
Dr. Bhardwaj Narayan Chaudhary, Dr. Rajeeva Mishra
Keywords
Related Articles
- EP ID EP251465
- DOI 10.9790/0853-1612095457
- Views 62
- Downloads 0
FamilialHypercholesterolemia: Screening, Diagnosis And Management of Patients.
Familial hypercholesterolemia (FH) is a genetic disorder of lipoprotein metabolism resulting in elevated serum low – density lipoprotein cholesterol leading to increased risk for premature cardiovascular disease (CVD). T...
Role of Neuroimaging in People Living with HIV and AIDS
Nervous system is commonly involved due to HIV infection. It is paramount to distinguish whether the neurologic deterioration is due to opportunistic infection or immune reconstitution or the effect of virus itself.MR im...
Paediatric Tracheostomy
Objective: To evaluate the indications of paediatric tracheostomy and associated morbidity within our patient population over the last one and a half years. Methods: We conducted a retrospective study of patients below 1...
Cutaneous Drug Reactions Reported In a Dermatology Outpatient Clinic of a Tertiary Care Hospital
Background:Cutaneous adverse drug reactions (CADR) are the most frequent serious adverse reactions reported in outpatient department of dermatology. Objective:The aim of the study to assess the prevalence and clinical sp...
A Study of Factors Contributing To Relapse in Alcohol Dependence and Intra Group Comparison of Factors Influencing Delay In Treatment Seeking After Relapse
Background: Alcoholism is a major mental and public health problem in developing countries like India. Social factors play vital role in unfolding of alcohol use disorders in any given population. Several factors beyond...