Screening of Anti-inflammatory Effect of Venlafaxine in Wistar Albino Rats
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2017, Vol 5, Issue 4
Abstract
Abstract: The aim is to evaluation of anti-inflammatory effect of Venlafaxine in Wistar Albino Rats.Wistar Albino rats were used in the study. Total 18 rats were divided into three groups each of 6 rats. G-A (Control), G-B- Aspirin (300 mg/kg) and G-C (Venlafaxine (50 mg/kg). All the drugs given 30 min before induction of paw inflammation by Carrageenan. Data was expressed by MEAN±SD and percentage (%). SPSS software was used for statistical analysis of data.Rats treated with standard and test drug showed significant difference compared to control group. Aspirin showed significant anti-inflammatory effect compared to Venlafaxine group. Similar results were observed in percentage of inflammation and reduction in percentage of inflammation. Venlafaxine produced anti-inflammatory action in paw model in rats. The anti-inflammatory effect of test drug is similar to Aspirin. Keywords:Anti-inflammatory,Aspirin, Carrageenan, Paw edema, Percentage of inhibition, Venlafaxine
Authors and Affiliations
Ganesh V, Mohamed Gani A, Sandeep V, SarathBabu K
Keywords
Related Articles
- EP ID EP372277
- DOI -
- Views 45
- Downloads 0
Control of Cystic Artery Using Monopolar Electrocautery in Laparoscopic Cholecystectomy: Our Experience
Abstract: The objective was to study the use of monopolar electrocautery for securing hemostasis of cystic artery in patients undergoing laparoscopic cholecystectomy. This was a retrospective observational study that was...
Status of Periodontal Health of Patients in the Drepanocyteurs at the Bamako Dreponocytosis Research Center (CRLD) in Mali: 446 Observations
Abstract: Sickle cell anemia or sickle cell anemia is a chronic, inherited, autosomal recessive inherited hemolytic disease that may be a risk factor for periodontal disease. The objective of this study is to evaluate th...
Characterization and Antibiogram of Klebsiella spp. Isolated from Clinical Specimen in a Rural Teaching Hospital
Klebsiella spp. is ubiquitous in nature. They inhabit the environment and intestinal tract of humans and animals. Klebsiella spp causes variety of healthcare associated infections including pneumonia, urinary tract infec...
Risk Factors and Outcome of Recurrent Ischemic Stroke-A Prospective Study in a Tertiary Care Hospital
Abstract: Cerebrovascular disease CVD is the most common disease group among all the neurological diseases. The prevalence of strokes in India is increasing as found in community-based studies. We in the present study tr...
Closed Primary Intramedullary Nailing for Elderly Paediatric Diaphyseal Forearm Bone Fracture
The current study was undertaken to assess the results of primary closed nailing in fracture shaft radius and ulna in elderly paediatric age group. Though in Paediatric age group the bones have a capacity to remodel when...