Screening of Antidepressant Effect of Hydro Ethanolic Extract of Caryoytaurens on Wistar Rats
Journal Title: Scholars Academic Journal of Pharmacy - Year 2017, Vol 6, Issue 4
Abstract
Abstract:A person’s thoughts, behavior, feelings and sense of wellbeing are important acts for the good sustainable life in the society and also for the personal life. Low mood, exercise rumination of negative thoughts, misery, apathy and pessimism, low self-esteem, feeling of guilty adequacy and ugliness ,indecisiveness ,loss of motivation, anhedonia, loss of reward, these are the symptoms of depression, which is a leading disorder making the human life uncomfortable. Biologically depression is an extremely common psychiatric condition, about which a variety of neurochemical theories exist and for which a corresponding variety of different types of drugs are used for treatment. Imbalanced state of neurotransmitters serotonin, dopamine, and norepihephrine will lead to the depression and anxiety. By evaluation of traditional claim using modern scientific experimental methods, Aiming to develop a drug obtained from plant origin to treat depression using various experimental animal models. On the observation, exploratory behaviors of the animals towards the plant extract with the help of various models involving in the methodology, the antidepressant activity of chemical constituents present in the plant extract, and on admission of the drug to the experiment animals, conducting the exploratory methods, found the antidepressant activity in the extract. Keywords:Neurotransmitters, Psychiatric condition, Antidepressants, Anhedonia, Anxiety.
Authors and Affiliations
Pagadala Srinivas, R. S. Shobana, R. Preethi, M. Mohammad Azeem, Jalaludeen . , Vijay kumar Pathak, P. Muralidharan
Keywords
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