SENSITIVITY PATTERN OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS ISOLATED FROM SURGICAL SITE INFECTIONS
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 6
Abstract
Surgical site infections are an important cause of health care associated infections among surgical patients. Patients who develop surgical site infections have longer hospital stays, more expensive hospitalizations, and increased mortality. They are the second most commonly reported nosocomial infection and they count for approximately a quarter of all nosocomial infections. This was a retrospective study conducted at a tertiary care hospital in South India, from June 2010 to December 2011. Testing for Methicillin resistance was performed by modified Kirby Bauer Disc Diffusion method using Cefoxitin (30μg) as recommended by the Clinical and Laboratory Standard Institute. A total of 195 aerobic bacteria were isolated. 114 were Gram positive cocci (58.4%) and 81 were Gram negative bacilli (41.5%). The most common organism was S. aureus, with 69 isolates (31.2%). Out of 61 isolates of S. aureus, 12 (19.6%) were Methicillin resistant. Highest resistance was seen with Penicillin and least resistance to Vancomycin and Linezolid. Resistance to Ciprofloxacin was and Gentamicin was 75% and 58.3% respectively. But the alarming sign is the resistance to Cephalosporins group of antibiotics which was more than 50%. We did not find any resistance to Vancomycin and Linezolid. Several studies all over the world have well established that the early detection of Methicillin resistance is very essential in the prognosis of infections which are caused by S. aureus as many of these infections are life threatening. The regular surveillance of SSIs and monitoring of antibiogram of MRSA will help in formulating a definite antimicrobial policy and reduce the use of powerful antibiotics like Vancomycin and Linezolid and preserve them for the treatment of life threatening infections.
Authors and Affiliations
Dr. Rajesh Kamtikar*| MS General surgery, Assistant professor, Department of Surgery, Bidar Institute of Medical Sciences, Bidar, 585401, India, Dr. Nagaraj Mitra| MS General surgery, Senior resident, Department of Surgery, Bidar Institute of Medical Sciences, Bidar, 585401, India
Keywords
Related Articles
- EP ID EP3450
- DOI -
- Views 340
- Downloads 17
A STUDY OF ANTI-HYPERLIPIDEMIC ACTIVITY OF MARKETED FORMULATIONS OF TERMINALIA ARJUNA POWDER USING EXPERIMENTAL ANIMAL MODEL
Hyperlipidemia is a disorder of lipid metabolism which is major risk of coronary heart disease. Now a day’s synthetic drugs have been associated with number of side effects but herbal medicines have lipid lowering and an...
CYTOPROTECTIVE EFFICACY OF DRDE-07 AND DRDE-30 AGAINST CISPLATIN INDUCED NEPHROTOXICITY
Aim: The objective of the study was to investigate the cytoprotective action of DRDE-07 and DRDE-30 against cisplatin induced nephrotoxicity in mice. Subjects and Methods: Randomly bred Swiss female mice (25-30 g) were s...
ANTIBIOTIC RESISTANCE PATTERN OF BLOODSTREAM BACTERIAL ISOLATES FROM ENTERIC FEVER PATIENTS: A PROSPECTIVE CROSS-SECTIONAL STUDY
Background:Enteric fever continues to remain a major public health problem, especially in regions of South-East Asia due to poor sanitation and personal hygiene. Bangladesh open prone to enteric fever outbreaks and is an...
COMPARISON OF TYPHIDOT-EIA AND WIDAL TEST IN RESPECT TO POLYMERASE CHAIN REACTION AS DIAGNOSTIC PROCEDURES FOR EARLY DIAGNOSIS OF TYPHOID FEVER
Background: The public health burden of typhoid fever can be substantially reduced by early diagnosis and appropriate antibiotic therapy. Aim: This is a descriptive cross-sectional study; aimed to compare Typhidot-EIA t...
OPTIMIZATION OF RHAMNOLIPID BIOSURFACTNT PRODUCTION BY STREPTOMYCES MATENSIS (NBRC 12889T) USING PLACKETT-BURMAN DESIGN
Surfactants produced by microorganisms are known as biosurfactants. Biosurfactants are becoming important biotechnology products for industrial and medical applications due to their specific modes of action, low toxicity...