Sero-prevalence of Toxoplasmosis in Pregnant Women with Bad Obstetric History attending a rural tertiary care Hospital in West Bengal, India
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 11
Abstract
Background:-Toxoplasma gondii infection in pregnancy is associated with potentially tragic outcome in the foetus and newborn worldwide, despite it being preventable. The infection is acquired via ingestion of infected, undercooked meat or contaminated food or water or close contact with infected but asymptomatic cats. Transmission to the foetus occurs almost exclusively from the infected mothers during gestation resulting in congenital toxoplasmosis. Objective:- Study was conducted in 80 women with BOH, attending the antenatal clinic of the Burdwan Medical College & Hospital, West Bengal, India to determine the seropositivity of Ig M & Ig G antibodies of Toxoplasmosis, using commercially available enzyme-linked immunosorbent assay diagnostic kit. 20 antenatal women with previous history of normal deliveries acted as the controls. Results:- Of the 80 BOH ante-natal mothers, the overall sero-positivity was found to be 36 (45%) for Toxoplasma specific IgM antibodies with maximum sero-positivity of 44.44% (16/36) among 21-25 yrs mothers. Repeated abortions was the commonest outcome (66.66%, 24/36) followed by intra-uterine deaths (16.66 %, 04/36).Conclusion:- Systematic education and serological screening of pregnant women are the most reliable and currently available strategies for the prevention, diagnosis, and early treatment of the infection in the offspring.
Authors and Affiliations
Biswas Tanusri, Chattopadhyay Saswati
Keywords
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- EP ID EP421549
- DOI 10.9790/0853-1711122932.
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