SEROFREQUENCY OF HEPATITIS D VIRUS AMONG HEPATITIS B INFECTED PATIENTS, KHARTOUM STATE, SUDAN.
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2015, Vol 4, Issue 5
Abstract
Background: Hepatitis Delta virus (HDV) is a defective RNA virus dependent on Hepatitis B virus (HBV) infection for its replication and expression. It is estimated that approximately 5% of hepatitis B surface antigen (HbsAg) carriers in the world are HDV infected patients. HBV-HDV co-infection may lead to more severe acute disease and higher risks of fulminant hepatitis, cirrhosis, and hepatocellular carcinoma than those having HBV infection alone. Therefore, our study aimed to detect serofrequency of hepatitis D among hepatitis B infected patients. Materials and Methods: This was cross sectional study included known HBV infected patients, conducted Khartoum State, Sudan, during March to June 2015. HDV Antigen was detected using commercially available ELISA kit. Generated data were analyzed by using SPSS program. Results: A number of 90 patients who were HBsAg positive, attending Khartoum state hospitals, Sudan, were included in this study, aged between (20-79) years old, out of them 4(4.4%), were positive for HDV Ag, and all of them were males. There was no association between positive HDV Ag and risk factors such as Hemodialysis, blood transfusion, IV drug abuse, cupping as well as previous history of hepatocellular carcinoma. Conclusions: Although HDV had a low frequency in our area, it is important for healthcare providers and policy makers to plan preventive strategies for HDV spread as well as HBV prevention programs among high risk population. Further investigations with large scale specimen are recommended.
Authors and Affiliations
Nafisa Osman Mohammed| Microbiology department, Faculty of Medical Laboratory Sciences, Al Neelain University, Sudan., Nafisa Ahmed Ibrahim| lecturer, Microbiology department, Faculty of Medical Laboratory Sciences, Al Neelain University, Sudan., Wafa Ibrahim Elhag| Associate professor, Microbiology department, Faculty of Medical Laboratory Sciences, Al Neelain University, Sudan.
Keywords
Related Articles
- EP ID EP3645
- DOI -
- Views 334
- Downloads 19
EMULGEL: A NOVEL APPROACH TO TOPICAL DRUG DELIVERY
Emulgel is an emerging topical drug delivery system to which if more effort is done towards its preparations with more number of topically effective drugs it will prove a boon for derma care products and cosmetic produc...
LIQUID CRYSTALLINE SYSTEM: A NOVEL APPROACH FOR DRUG DELIVERY
Liquid crystaline system is a thermodynamically stable phase which is characterized by anisotropy. LC’s are also termed as mesophase as they exhibit isotropic properties and fluid-like behavior under some conditions (cha...
ORGANOGELS IN DRUG DELIVERY
Organogels are semi-solid systems, in which an organic liquid phase is immobilized by a three-dimensional network composed of self assembled, intertwined gelator fibers. The apolar phase gets immobilized within spaces...
Cervical Cancer–A Review Article
Cervical Cancer is malignant Carcinoma type of cancer originate in cervix region. The cervix is the narrow portion of the uterus where it joins with the top of the vagina. Most cervical cancers are squamous cell carcinom...
ANTIOXIDANT AND ANTIDIABETIC ROLE OF PETROSELINUM CRISPUM AGAINST STZ-INDUCED DIABETES IN RATS
Petroselinum crispum (Parsley) has been reported to have a number of possible medicinal attributes. The aim of this work is to evaluate the ameliorative effect of parsley aqueous extract (PAE) against STZ-induced diabeti...