Serological study of viral hepatitis
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 3
Abstract
Introduction Viral hepatitis is caused by hepatotropic virus like hepatitis A B C D E and G Viral hepatitis is a major public health problem in India which is hyperendemic for HAV and HEV The present study titled serological study of viral hepatitis is undertaken to detect the rate of different hepatitis viral infections also to identify coexistence of any of these viral hepatitis and an attempt is also made to detect the presence of other hepatitis B virus markers which would help in understanding the prognosis of hepatitisMaterial and Methods Serum samples were tested for detection of hepatitis A IgM hepatitis B surface antigen hepatitis C antibody and hepatitis E IgM antibody using specific ELISA kitsFor patients showing positive results to HBsAg tests further markers like antiHBs HBeAg and antiHBc were detected by ELISAResults A total of 2760 samples were screened for the presence of HAV HBV HCV and HEV And seropositivity was detected 67 cases were positive for HBsAg 27 12 for hepatitis A 355 2 each were positive for hepatitis C 069 and hepatitis E 17 respectively Of 2760 patients tested 2 coinfections occurred HAV along with HBV and HAV with HEVConclusion In this study a total of 2760 cases were screened for viral hepatitis infections The patients showed positivity to HAV HBsAg HCV HEV and some of the HBV markers And some co infections were also seen It is important to diagnose viral hepatitis to limit the spread of this contagious disease This is particularly important in the routine testing of potential blood donorsKeywords Hepatitis ELISA Seroprevalence Diagnosis
Authors and Affiliations
Rashmi P. Mahale, M. Raghauendra Rao, Sowmya G. S, Ranjijha Shankare Gowda
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