Seroprevalance of HBsAg, anti-HIV 1&2 and anti-HCV by chemiluminescence method - A hospital based study from 2007 to 2014
Journal Title: Journal of Medical and Scientific Research - Year 2015, Vol 3, Issue 1
Abstract
Introduction: Hepatitis B virus (HBV), human immunodeficiency virus 1&2 (HIV1&2) and hepatitis C virus (HCV) are major public health problem. Detection of hepatitis B surface antigen (HBsAg), antibodies to human immunodeficiency virus 1&2 and hepatitis C virus in patients (both inpatients and outpatients) can help in patient management. Screening of patient samples for HBsAg, anti-HIV 1&2 and anti-HCV is important in managing surgical and medical care. The objective is to know prevalence of hepatitis B surface antigen (HBsAg), antibodies to HIV 1&2 and HCV inpatient and outpatient, their gender, age wise distribution and department wise distribution. Material & methods: The present study was conducted in the Department of Microbiology, Krishna Institute of Medical Sciences (KIMS), Secunderabad, Telangana, during a study period of 8 years from January 2007 to December 2014. It is a cross sectional study. It is a laboratory based study, no clinical correlation has been done. The positive/reactive samples were studied for their gender, age group and department. Analysis was done on a yearly basis. A cumulative data of 8 years is being presented. The samples were screened by enhanced chemiluminescence (ECLIA) technology by using an instrument, Vitros ECiQ(Ortho Clinical Diagnostic). Results: 1,00,590 patients were screened 1,805 (1.79 %) were positive for HBsAg. 92,819 patients screened 501(0.53%) were reactive for HIV 1&2 antibodies. 61,072 screened 744(1.21%) were reactive for HCV infection. The seroprevalence of all viral markers is more in males than females. In the present study seropositivity of HBsAg was higher in 41-50 year & 51-60 years followed by 31-40 years & 61-70 years. Highest prevalence of HIV was observed in 31-40 years followed by 41-50 years. Seropositivity of HCV was higher in 51-60 years followed by 41-50 years & 61-70 years. Conclusion: Emphasizes the need of screening of viral markers for inpatients and out patients. Adherence to universal precautions
Authors and Affiliations
Bilolikar AK, Latha BM, Reddy SG, Vanaja S, Imtiyaz MD, Chowdary RD
Keywords
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- EP ID EP604586
- DOI 10.17727/JMSR.2015/3-001
- Views 103
- Downloads 0
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