Seroprevalence of Chikungunya cases in a tertiary care hospital in Mumbai
Journal Title: Medpulse International Journal of Microbiology - Year 2017, Vol 4, Issue 1
Abstract
Background: Chikungunya is a viral disease characterized by joint pain for prolonged duration. The year 2006 witnessed an extensive outbreak of Chikungunya cases in India. The total number of 13,90,322 suspected Chikungunya fever cases were reported in 2006 and 64,057 were reported in 2016 including Maharashtra state and it persists as a major public health problem till date. Objective: To determine the seroprevalence, clinical presentation and seasonal trends of Chikungunya infection in a tertiary care hospital in Mumbai. Materials and Methods: A retrospective study was conducted at a tertiary care hospital in Mumbai. Serum samples were collected from 344 suspected cases of Chikungunya fever and tested for Chikungunya IgM antibodies by ELISA (from NIV, Pune) over a 5 year period from June 2011 to May 2016. Results: Of the 344 serum samples tested, 69 (20.06%) were positive for Chikungunya IgM antibodies. The most affected age group was 31 to 45 years (42.03%), followed by 16 to 30 years (36.23%). Of the seropositive cases, all presented with fever and joint pain. Headache, bodyache, joint swelling and rash were seen in 94.2%, 72.46%, 39.13% and 17.39% respectively. The maximum number of cases were seen in the period from September to November (36.23%), followed by the period from December to February (31.88%). Conclusion: The seroprevalence of Chikungunya cases in our study was 20.06% with high prevalence in the late monsoon and post monsoon months. This reiterates the fact that Chikungunya continues to be a major health concern in our setting and indicates the need for appropriate strategies to reduce the severity of disease.
Authors and Affiliations
Sujata Baveja, Shaikh Mohd Habeeb, Anita Ramchandran, Dilip Turbadkar, Chaya A Kumar, Mrudul Randive
Keywords
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- EP ID EP487284
- DOI 10.26611/1008411
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