Serum C - reactive protein in Normal Pregnancy and Preeclampsia- a Comparative Study
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2015, Vol 3, Issue 9
Abstract
The aim and objective of the study is to find out the correlation between C - reactive protein (CRP) in normal pregnancy with that of preeclampsia as well as to study the level of C - reactive protein in relation to the severity of the preeclampsia and its pregnancy outcome. A Hospital based prospective comparative study was performed on 100 singleton pregnant women after 20 weeks of gestation include 50 preeclamptic (25 mild and 25 severe) patients and 50 normotensive pregnant women as controls were selected for the study in the department of Obstetrics & Gynaecology, Assam Medical College and Hospital for a period of one year. After initial assessment of every patient, blood sample was collected in a sterile empty vial. Serum CRP levels were measured by high CRP sensitivity kit using Particle Enhanced Turbimetric Immunoassay (PETIA) Technique. Clinical outcome were evaluated. Statistical analysis was done using Student’s t-test. The mean level of serum CRP in preeclamptic patients was 2.1 + 1.36 mg/dl and that in normotensive pregnant women was 0.39 + 0.09 mg/dl ( p-value < 0.0001). And mean level of serum CRP in mild preeclamptic patients was 1.08 + 0.53 mg/dl and severe preeclamptic patients was 3.12 + 1.16 mg/dl ( p < 0.001 ). We therefore conclude that CRP level is raised in preeclampsia than normal pregnancy and also these results suggests that CRP levels are increased more in severe preeclampsia than mild preeclampsia. Thus, CRP can be used as a useful parameter for the assessment of preeclampsia. Keywords: Preeclampsia, normal pregnancy, C - reactive protein
Authors and Affiliations
Dr. Karuna Kanta Das, Prof. Kailash Bhattacharyya, Dr. Mun Konwar
Keywords
Related Articles
- EP ID EP372952
- DOI -
- Views 58
- Downloads 0
Prevalence and Antibiogram of Gram Positive Organism Isolated from Patients of Urinary Tract Infection
Abstract: Urinary tract infection (UTI) is one of the most frequent types of nosocomial infections and probably affects about one-half of all people during their lifetimes. The predominant pathogen responsible for UTI is...
A Prospective Randomised Study for Comparison of Total Laparoscopic Hysterectomy and Non Descent Vaginal Hysterectomy for the Treatment of Benign Diseases of Uterus
Abstract: To compare the surgical outcome of two techniques of hysterectomy- TLH and NDVH. 40 women with benign diseases of uterus were randomized into two groups, 20 in each group. In these patients, intraoperative para...
Foreign Bodies in Aerodigestive Tract
Abstract: Foreign bodies in aero digestive tract are more common in children. The objective of our study is to know the nature of foreign bodies, age, sex distribution and site of lodgement. A prospective study was condu...
Antioxidant and free radical scavenging activities of root extracts of Muntingia Calabura
The in vitro antioxidant properties of different extracts (water, alcohol, alcohol: water, hexane or chloroform extract) of Muntingia Calabura roots were evaluated using various assays. The water and alcohol: water (1:1...
Crisis Management of Perioperative Bronchospasm in a Neonate with Sepsis
Abstract:Bronchospasm in association with anaesthesia may appear as an entity in its own right or be a component of another problem such as anaphylaxis. It may present with expiratory wheeze, prolonged exhalation or, in...