Sesquiterpenoids from Illicium difengpi and their Chemotaxonomic Significance
Journal Title: Tropical Journal of Natural Product Research - Year 2017, Vol 1, Issue 2
Abstract
Illicium difengpi (family Illiciaceae) is a known medicinal plant used in Ancient Chinese medicines for the treatment of diseases and infections. The purpose of the present study was to investigate the chemical constituents of the stem bark of Illicium difengpi and determine their chemotaxonomic significance. The stem barks of I. difengpi were purchased from Caitongde Pharmacy and authenticated by Professor Lian-na Sun. The 80 % ethanol extract was fractionated with silica gel column chromatography (C.C.) and compounds were isolated with ODS C.C., silica gel (SiO2) C.C. and preparative/semipreparative HPLC from the fractions. The chemical structures were elucidated by NMR spectroscopy and mass spectrometry, as well as the comparison of spectra data with that reported in the literature. The present phytochemical investigation on Illicium difengpi led to the isolation and characterization of 13 sesquiterpenoids, including five eudesmanes, three cadinanes, two bullatanes and three other types of sesquiterpenoids. All compounds except compound 2 were isolated from this species for the first time. In addition, compounds 1, 3, 4, 5, 7, 8, 11 and 13 have not been reported in any species of the genus Illicium and the family Illiciaceae. Sesquiterpenoid compounds from I. difengpi may have the potential to produce new insights into the historical debate concerning the systematic position and phylogenetic relationship of the genus Illicium.
Authors and Affiliations
Wan-sheng Chen
Keywords
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- EP ID EP349891
- DOI 10.26538/tjnpr/v1i4.
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