Severe Human parainfluenza type 2 virus pneumonitis in immunocompetent host; A case series of 10 patients
Journal Title: IOSR Journal of Dental and Medical Sciences (IOSR-JDMS) - Year 2018, Vol 17, Issue 10
Abstract
Background: Human parainfluenza viruses are the major cause for respiratory illness in human and among HPIV type 2 rarely affect an immunocompetent host. A changing pattern of clinical spectrum of this virus type can pose a serious threat in the future. Patients and Methods: We report 10 patients who were admitted to our institute with extensive involvement of lower respiratory tract and were found to be positive for HPIV type 2 virus during a period of 6 months from February 2018 to august 2018. The diagnosis was confirmed by PCR from throat swab and after exclusion of any immunocompromised state of the patient. Results: All patients initially presented with fever, severe respiratory difficulty and Positive throat swab PCR for Human parainfluenza virus type 2 strain also all patients were screened for H1N1, scrub typhus and other causes of bilateral pneumonitis which are quite common in the geographical area. Blood investigations showed variable total leukocyte count, elevated liver enzymes (n=7) and chest radiograph showing bilateral infiltrate (n=10), three out of ten required ventilator support and two patients died of this disease who were critically ill. Conclusions: Human parainfluenza virus type 2 not only involves an immunocompetent host but can be associated with high mortality rate if not managed aggressively.
Authors and Affiliations
Vinay Tuteja, C. L. nawal, R. S chejara, Aradhana singh, Rajbeer singh
Keywords
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- EP ID EP402575
- DOI 10.9790/0853-1710093133.
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