SGLT2 inhibitors – new oral hypoglycemic drugs
Journal Title: Postępy Nauk Medycznych - Year 2013, Vol 26, Issue 3
Abstract
The prevalence of diabetes increases worldwide and glycemia in many patients Dos not meet the targets precised by American or Polish Diabetes Association. These two fact stimulate development of new treatment possibilities in diabetes. One of them, described below, are kidney sodium and glucose transporter inhibitors. From the one side they increase urinary glucose excretion (mimicking the natural defense mechanism of the organism) resulting in decrease of glycemia and in negative energy balance, favoring decrease of weight, from the other icreased sodium excretion decreases blood pressure. The price for that effects is however increased frequency of genitourinary tract infections. The first marketed drug belonging to this group is dapagliflosine.
Authors and Affiliations
Bernadetta Kałuża, Edward Franek
Keywords
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