Skin-mucous side effects of the retinoids in the therapy of acne vulgaris
Journal Title: Postępy Nauk Medycznych - Year 2012, Vol 25, Issue 10
Abstract
<b>Introduction. </b>Acne vulgaris is one of the most commonly diagnosed dermatosis in patients aged 11-30 years. It is believed to be found in about 80% of patients in this age group but if considering forms of mild intensity, even 100% of adolescents may be affected.<br><b>Aim, materials, methods.</b> The aim of this work was to access the skin parameters such as: moisturisation, transepidermal water loss (TEWL) and others skin-mucous side effects during oral treatment with isotretinoin. The tests were performed in 155 patients treated for different clinical forms of acne with an oral isotretinoin preparation in the Dermatology Clinic of the Medical University of Silesia in Katowice in 2009-2011 – I group and the patients treated with oral isotretinoin 2 and 5 years ago – II group. The control group consisted of 40 healthy individuals.<br><b>Results, conclusions.</b> On the basis of performed analyses it was concluded that the new therapy schema is the most advantageous form of isotretinoin dosing and it involves the use of a constant drug dose – 0.4-1.0 mg/kg b.m./day without modification during treatment. The effects of such a model of treatment are most efficient, the treatment shortest and the mucosa-skin symptoms are similar, even less pronounced than for other schema of retinoid dosing.
Authors and Affiliations
Beata Bergler-Czop, Ligia Brzezińska-Wcisło
Keywords
Related Articles
- EP ID EP54312
- DOI -
- Views 161
- Downloads 0
Identification of rod-shaped Gram-negative bacilli of Enterobacteriaceae family by MALDI-TOF mass spectrometry
Introduction. Matrix assisted laser desorption ionization-time of flight mass spectrometry is a new rapid method for identification of microorganisms isolated from clinical specimens.Aim. The aim of the study was to comp...
Powikłania związane z występowaniem uchyłka Meckela jako postaci przetrwałego przewodu żółtkowo-jelitowego
Uchyłek Meckela jest najczęstszą wadą wrodzoną przewodu pokarmowego. Występuje na skutek nieprawidłowego zaniku przewodu żółtkowo-jelitowego, do którego powinno dojść między 7 a 8 tygodniem życia płodowego. Nie dokonanie...
Is there really an epidemic of autism?
Autistic disorder, pervasive developmental disorder-not otherwise specified and Asperger syndrome belong to a group of disorders called autism spectrum disorders (ASDs). In the past 25 years, an increase in the prevalenc...
Przezskórne leczenie jatrogennych tętniaków rzekomych tętnicy udowej
Wstęp. Badania i zabiegi przeznaczyniowe są powszechnie stosowane w kardiologii i radiologii zabiegowej. Umożliwiają dokładną diagnostykę i wewnątrznaczyniowe leczenie chorób naczyń.Zabiegi przeznaczyniowe zaliczane są d...
Plasma vitamin D levels in obese children: relationship with selected anthropometric and metabolic parameters
Introduction. The prevalence of overweight and obesity is increasing worldwide, particularly among children and adolescents. Investigations report a correlation between serum 25(OH)D level and body mass. Plasma 25(OH)D c...