Significance of Hyponatremia in Decompensated Chronic Liver Diseases
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 2
Abstract
To assess the frequency of serum sodium and its correlation with the severity of chronic liver diseases. The Study Design is Prospective Study. The Place and Duration of Studyare Dr D Y Patil Hospital and Research Institute, Kolhapur Maharashtra between October2013 to May 2015. The Methodology isa total of 100 patients with decompensated alcoholic liver disease were enrolled and their serum sodium was measured. Relationship of hyponatremia was correlated with severity of decompensated chronic liver disease. In Results the Out of 100 patient, 73(73%) patients had serum sodium < 130meq/l, 17 (17%) had serum sodium levels between 130-135 meq/l and 10 patients > 135meq/l. Ascities (96%) was the most common complication in patient with hyponatraemia. Hepatic Encephalopathy was present in 34(34%) patients. Hepatorenalsyndrome (41%) and bleeding complication like variceal bleeding was present in 37(37%) patient. Mortalityrate (35%) was also on the higher side with patients having serum sodium <130meq/L. The Conclusion in this study is Hyponatraemia was the common feature in the patient with decompensated alcoholic liver disease. The existence of serum sodium concentration with <130mmol/L was associated with greater frequency of complication and mortality. Keywords: Hyponatraemia, Hepatic Encephalopathy.Hepatorenal syndrome.
Authors and Affiliations
Dr. Rajesh Khyalappa, Dr. Anoop Bardeskar
Keywords
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