SIGNIFICANCE OF SPOT URINE PROTEIN CREATININE RATIO VERSUS 24-HOUR URINE PROTEIN ANALYSIS AND THEIR CORRELATION IN QUANTIFICATION OF PROTEINURIA IN HYPERTENSIVE PREGNANT WOMEN- A PROSPECTIVE OBSERVATIONAL STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 13
Abstract
BACKGROUND We wanted to evaluate the efficacy of protein creatinine ratio in quantification of proteinuria in hypertensive pregnant women between 20 to 40 weeks to study the correlation between protein creatinine ratio of spot urine sample and the protein content of 24 hours urine collection. MATERIALS AND METHODS Hypertensive pregnant women between 20 to 40 weeks were included in the study. Protein/creatinine ratio was obtained from urine samples collected soon after 24-hours urine collection. Sensitivity and specificity, positive and negative predictive values of the protein/creatinine ratio for significant proteinuria (≥ 300 mg) were calculated, based on 24-hours urine total protein. RESULTS There was a strong correlation between the spot P/C ratio and 24-hour urine protein excretion (r = 0.715; P < .0001). The optimal spot P/C ratio cut-off point was 0.35 for 300 mg/24 h of protein excretion (preeclampsia), with a sensitivity, specificity, positive predictive value, and negative predictive value and accuracy of 91.8%, 93.33%, 98.73%, 66.66% and 92% respectively. CONCLUSIONS A significant correlation between the spot urine P/C ratio and 24-hour urine protein excr
Authors and Affiliations
Rekha Reddy, Sireesha Sireesha, Manjula Manjula, Shruthi Manvikar
Keywords
Related Articles
- EP ID EP615897
- DOI 10.18410/jebmh/2019/227
- Views 82
- Downloads 0
FUNCTIONAL OUTCOME EVALUATION OF PHALANGEAL AND METACARPAL FRACTURES TREATED WITH JESS FIXATION
BACKGROUND Fractures of metacarpals and phalanges are the most common fractures of the upper extremity and account for 10% of total such cases. The outer rays of the hand are most commonly injured. The incidence of metac...
STUDY OF OUTCOME OF MODIFIED SHOELACE REPAIR DONE FOR DIVARICATION OF RECTI
BACKGROUND Divarication of recti is characterised by thinning and widening of linea alba combined with laxity of the ventral abdominal musculature. It is often misclassified as a primary ventral hernia. But the musculofa...
EFFICACY, SAFETY AND QUALITY OF LIFE OUTCOMES OF PALONOSETRON, RAMOSETRON AND GRANISETRON AS A PART OF ANTIEMETIC THERAPY IN PREVENTION OF CHEMOTHERAPY INDUCED NAUSEA AND VOMITING- A RANDOMISED COMPARATIVE TRIAL
BACKGROUND 5-HT3 receptor antagonists have potent antiemetic effect in chemotherapy induced nausea and vomiting. The present study was conducted to study and compare the efficacy and safety of ramosetron, palonosetron an...
ROLE OF MULTIPHASE CT IN DIFFERENTIATING PLEOMORPHIC ADENOMA FROM OTHER PAROTID NEOPLASMS
BACKGROUND Pleomorphic adenoma of parotid gland shows mild enhancement immediately after IV contrast injection. This property can be used in differentiating it from other parotid neoplasms. The aim of this study was to r...
MORPHOLOGICAL PATTERN OF ANAEMIA IN GERIATRICS: HOSPITAL BASED STUDY OF 126 CASES
BACKGROUND Anaemia is a common public health concern in geriatric age group (More than 60 yrs. of age) and can have significant morbidity and mortality. WHO criteria to determine anaemia is hemoglobin level <13g/dl in ma...