SIGNIFICANCE OF SPOT URINE PROTEIN CREATININE RATIO VERSUS 24-HOUR URINE PROTEIN ANALYSIS AND THEIR CORRELATION IN QUANTIFICATION OF PROTEINURIA IN HYPERTENSIVE PREGNANT WOMEN- A PROSPECTIVE OBSERVATIONAL STUDY
Journal Title: Journal of Evidence Based Medicine and Healthcare - Year 2019, Vol 6, Issue 13
Abstract
BACKGROUND We wanted to evaluate the efficacy of protein creatinine ratio in quantification of proteinuria in hypertensive pregnant women between 20 to 40 weeks to study the correlation between protein creatinine ratio of spot urine sample and the protein content of 24 hours urine collection. MATERIALS AND METHODS Hypertensive pregnant women between 20 to 40 weeks were included in the study. Protein/creatinine ratio was obtained from urine samples collected soon after 24-hours urine collection. Sensitivity and specificity, positive and negative predictive values of the protein/creatinine ratio for significant proteinuria (≥ 300 mg) were calculated, based on 24-hours urine total protein. RESULTS There was a strong correlation between the spot P/C ratio and 24-hour urine protein excretion (r = 0.715; P < .0001). The optimal spot P/C ratio cut-off point was 0.35 for 300 mg/24 h of protein excretion (preeclampsia), with a sensitivity, specificity, positive predictive value, and negative predictive value and accuracy of 91.8%, 93.33%, 98.73%, 66.66% and 92% respectively. CONCLUSIONS A significant correlation between the spot urine P/C ratio and 24-hour urine protein excr
Authors and Affiliations
Rekha Reddy, Sireesha Sireesha, Manjula Manjula, Shruthi Manvikar
Keywords
Related Articles
- EP ID EP615897
- DOI 10.18410/jebmh/2019/227
- Views 76
- Downloads 0
EPIDURAL EPITHELOID HEMANGIOMA OF CERVICAL SPINE PRESENTING WITH COMPRESSIVE MYELOPATHY: A CASE REPORT
Cervical spinal epidural epitheloid hemangioma is a rare entity. All epidural spinal cord tumors should be considered in differential diagnosis. Surgery is indicated when there is compression over the cord or spinal inst...
HUMAN CORONARY ARTERIES- A STUDY BASED ON GROSS ANATOMY AND CORONARY CAST
BACKGROUND Present study is an attempt to throw light upon the coronary arterial pattern, variations in arterial distribution and extent of intercoronary anastomosis and arterial preponderance in different age groups. MA...
IMMUNOEXPRESSION PATTERN OF P16 & P53 IN ORAL EPITHELIAL DYSPLASIA AND ORAL SQUAMOUS CELL CARCINOMA
BACKGROUND Oral squamous cell carcinoma (OSCC) has become one of the leading causes of death mostly in developing countries with worldwide estimated incidence of around 3,00,000 and accounts for more than 95% of oral can...
PRIMARY EXTRANODAL NON-HODGKIN’S LYMPHOMA OF LEFT TONSIL: A CASE REPORT
Lymphoma encompasses a complex group of malignancies of the lymphoreticular system. Non-Hodgkins lymphoma of the Waldeyer’s ring is a rare entity. Chemoradiation gives a better prognosis. Here a case of unilateral palati...
A STUDY OF VARIATION OF TOTAL LEUCOCYTE COUNT AND PLATELET COUNT WITH DIFFERENT PHASES OF MENSTRUAL CYCLE
BACKGROUND Menstrual cycle is a physiological state which is associated with numerous changes affecting the hormone levels. The blood counts change especially the leucocyte count and the platelet count, which may give an...