Skin Lesions after Kidney Transplantation: An updated Review Including Recent Rare Cases
Journal Title: International Journal of Transplantation Research and Medicine - Year 2016, Vol 2, Issue 1
Abstract
Skin disease is a significant cause of morbidity in chronically immunosuppressed patients, including organ transplant recipients. Cutaneous neoplasms are much more common in renal transplant recipients than in the general population, and are the most common malignancies in these patients. Better surgical techniques and recent advances in immunosuppressive therapy allow patients to survive for many years, free from any complications due to rejection. However, cutaneous lesions can be a significant problem for this group of patients. Immunosuppression predisposes them to infections, as well as malignant tumors. The review of the current literature on skin manifestations in renal transplant recipients is done with emphasis on recent rarely seen clinical manifestations.
B-Cell Targets to Treat Antibody-Mediated Rejection in Transplantation
Abstract: Antibody-mediated rejection (AMR) in allograft transplantation can be defined with a rapid increase in the levels of specific serological parameters after organ transplantation, presence of donor specific antib...
Mycotic Aneurism in Renal Transplantation Associated to Persistent Leucopenia. Case Report and Review of the Literature
Introduction The infectious aneurysm in kidney transplant carriers constitutes 1-3% of all the reported aneurysms. In this population the frequency of infectious complications is high due to the presence of over immunosu...
Blockade of ASC but not NLRP3 Inhibits DC Proliferation and T cell Activation in Response to Alloantigen
The NLRP3 inflammasome is a multimeric protein complex consisting of the sensor molecule NACHT, LRR and PYD domains-containing protein 3 (NLRP3), the adaptor molecule Apoptosis-associated speck-like protein containing a...
Donation Over Age 70 and Older İs an Obstacle for Kidney Transplantation?
Abstract: The profound organ shortage has resulted in longer waiting times and increased mortality for those awaiting kidney transplantation. Consequently, patients are turning to older living donors. It is unclear if an...
Influence of Metronidazole on Oral Busulfan Test Dose
Abstract: Individualization of busulfan (BU) dosing during pre-transplant conditioning for hematopoietic stem cell transplantation (HSCT) has been performed worldwide for more than a decade. The pharmacokinetic parameter...