Soil Transmitted Helminth Infections and its Association with Haemoglobin Levels in India: A Meta-analysis
Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 6
Abstract
ABSTRACT Introduction: Soil Transmitted Helminth (STH) infections affect some of the poorest countries in the world. India is one of the most severely affected countries by these parasitic infections. They primarily affect children by impairing nutritional status, cognitive ability and overall development. Lower haemoglobin levels are a very common symptom associated with Helminth infections. Aim: The present study was conducted to analyse the effect of STH infections on haemoglobin levels in India. Materials and Methods: A systematic search of PubMed and Web of Science was carried out. We systematically reviewed the literature to identify studies reporting data on STH infection associated anaemia without any bar on language or date of publication. Full text studies reporting data on STH infection associated anaemia in humans were considered for final analysis. Results: Careful screening resulted in 16 publications that met the eligibility criteria out of which six were case reports and ten were cross-sectional studies that reported data on helminth infections and haemoglobin levels. Odds ratio analysis of five cross-sectional reports indicated that Helminth infections are three times (OR-2.8, CI-95%, 2.4-3.4) more likely to be associated with lower haemoglobin levels as compared to uninfected population. An analysis of case reports indicated severe to moderate anaemia in all patients. Conclusion: Helminth infections are often associated with lower haemoglobin levels resulting in lower cognitive development. We have found evidence that helminth infections are associated with lower haemoglobin levels in Indian population. Implications of Key Findings: This study can provide a guideline to clinicians and healthcare professional in identifying a baseline for haemoglobin level associated with STH infection associated anaemia and might lead to more comprehensive analysis of reasons for anaemia, growth stunting and cognitive impairment in at risk Indian population.
Authors and Affiliations
Nasir Salam, Mohammad Fareed
Keywords
Related Articles
- EP ID EP605031
- DOI 10.7860/JCDR/2019/40681.12950
- Views 135
- Downloads 0
Validation of Gujarati Translated Version of Stroke Impact Scale
ABSTRACT Introduction: Stroke Impact Scale (SIS) is an outcome measure for assessment of quality of life in post stroke patients. SIS version 3.0 and SIS-16 has been translated by MAPI Research Institute into various lan...
Comparative Analysis of External Quality Assessment Results from Dimension EXL 200 and VITROS® 4600
ABSTRACT Introduction: In order to maintain a strict control over the results generated in clinical chemistry laboratories, a number of procedures are followed to maintain the quality of results. The procedures followed...
Association of Manual Weight Lifting Tasks with Low Back Pain: A Pilot Study
ABSTRACT Introduction: Manual Weight Lifting (MWL) and Low Back Pain (LBP) become closely interrelated when lifting tasks are performed without adhering to lifting norms. Maximum trauma during MWL is encountered by lower...
Hyponatremia as a Mortality Predictor of Severe Malaria: A Hospital Based Cross-sectional Study
ABSTRACT Introduction: It is well known that hyponatremia is common in severe malaria. However, there is scanty and conflicting literature regarding hyponatremia as a predictor of mortality in severe malaria. Aim: To det...
EBUS- TBNA-Initial Experience from a Tertiary Care Center in Southern India
ABSTRACT Introduction: Conventional trans bronchial needle aspiration is associated with a low diagnostic yield in mediastinal adenopathy. Ultra sound guidance improves the diagnostic yield in these cases. Though linear...