Soil Transmitted Helminth Infections and its Association with Haemoglobin Levels in India: A Meta-analysis

Journal Title: Journal of Clinical and Diagnostic Research - Year 2019, Vol 13, Issue 6

Abstract

ABSTRACT Introduction: Soil Transmitted Helminth (STH) infections affect some of the poorest countries in the world. India is one of the most severely affected countries by these parasitic infections. They primarily affect children by impairing nutritional status, cognitive ability and overall development. Lower haemoglobin levels are a very common symptom associated with Helminth infections. Aim: The present study was conducted to analyse the effect of STH infections on haemoglobin levels in India. Materials and Methods: A systematic search of PubMed and Web of Science was carried out. We systematically reviewed the literature to identify studies reporting data on STH infection associated anaemia without any bar on language or date of publication. Full text studies reporting data on STH infection associated anaemia in humans were considered for final analysis. Results: Careful screening resulted in 16 publications that met the eligibility criteria out of which six were case reports and ten were cross-sectional studies that reported data on helminth infections and haemoglobin levels. Odds ratio analysis of five cross-sectional reports indicated that Helminth infections are three times (OR-2.8, CI-95%, 2.4-3.4) more likely to be associated with lower haemoglobin levels as compared to uninfected population. An analysis of case reports indicated severe to moderate anaemia in all patients. Conclusion: Helminth infections are often associated with lower haemoglobin levels resulting in lower cognitive development. We have found evidence that helminth infections are associated with lower haemoglobin levels in Indian population. Implications of Key Findings: This study can provide a guideline to clinicians and healthcare professional in identifying a baseline for haemoglobin level associated with STH infection associated anaemia and might lead to more comprehensive analysis of reasons for anaemia, growth stunting and cognitive impairment in at risk Indian population.

Authors and Affiliations

Nasir Salam, Mohammad Fareed

Keywords

Related Articles

The Efficacy of 311-NM Narrowband Ultraviolet B (NB-UVB) and Topical Agents or Lasers Combination Therapy versus NB-UVB Monotherapy for Vitiligo: A Systematic Review and Meta-analysis of Randomised Controlled Trials

ABSTRACT Introduction: Even though there is the availability of multiple treatment modalities for vitiligo still its treatment remains challenging. Combination therapies of Narrowband Ultraviolet B (NB-UVB) and various t...

Recall of Complications and Satisfaction of Consent in Mandibular Third Molar Surgery: A Randomised Controlled Single Blind Study

ABSTRACT Introduction: Informed consent prior to any medical procedure is important for legal, ethical and administrative reasons. Informed consent intends to improve the patients’ knowledge which will allow involvement...

Tiny Creature in Oral Cavity: A Case Report

Oral cavity is nidus of much pathology. Some may arise due to altered eating habits such as meat, uncooked food etc. The parasitic infections arising from ingesting uncooked pork (larva of pork tapeworm) called as cystic...

Effect of Mobile Phone Usage on Nickel Ions Release and pH of Saliva in Patients Undergoing Fixed Orthodontic Treatment

Introduction: Hand held mobile phones are presently the most popular means of communication worldwide and have transformed our lives in many aspects. The widespread use of such devices have resulted in growing concerns r...

Musculoskeletal Disorders and Quality of Life of Sugarcane Farmers in the Northeast of Thailand: A Cross-sectional Analytical Study

ABSTRACT Introduction: Musculoskeletal Disorders (MSDs) were directly associated with Quality of Life (QOL). It could cause various adverse consequences to daily life function, psychological health, work capacity and inc...

Download PDF file
  • EP ID EP605031
  • DOI 10.7860/JCDR/2019/40681.12950
  • Views 151
  • Downloads 0

How To Cite

Nasir Salam, Mohammad Fareed (2019). Soil Transmitted Helminth Infections and its Association with Haemoglobin Levels in India: A Meta-analysis. Journal of Clinical and Diagnostic Research, 13(6), 12-16. https://europub.co.uk/articles/-A-605031