Solitary lingual neurofibroma. A rare case report
Journal Title: ΑΡΧΕΙΑ ΕΛΛΗΝΙΚΗΣ ΣΤΟΜΑΤΙΚΗΣ ΚΑΙ ΓΝΑΘΟΠΡΟΣΩΠΙΚΗΣ ΧΕΙΡΟΥΡΓΙΚΗΣ - Year 2016, Vol 17, Issue 1
Abstract
Neurofibroma is a rare benign, non-odontogenic tumour of the oral cavity. It consists of a wide variety of Schwann cells, perineural cells and fibroblasts. Clinically, neurofibromas may present as slow-growing, pedunculated or sessile tumours, which are usually asymptomatic. They may occur either as solitary lesions, or as individual manifestations of von Recklinghausen multiple neurofibromatosis. In this study, we present the case of a patient with a solitary, asymptomatic, submucosal swelling of the lateral surface of the tongue. Surgical resection was the treatment of choice. In histopathological terms, this lesion was a neurofibroma. This was confirmed by its positive immunoreactivity to S-100 protein, which is indicative of neural origin. The differential diagnosis and treatment of the lesion are discussed in detail, along with the clinical and laboratory findings. What makes this case report especially interesting is exactly the rarity of oral neurofibromas.
Authors and Affiliations
Eleonora BLIOUMI, Chrysoula TSOBANIDOU, Stefanos STEFANIDIS, Lampros ZOULOUMIS
Keywords
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