Some Altered Trace Elements in Patients with Polycystic Ovary Syndrome
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 20, Issue 3
Abstract
Background: Insulin resistance is common in patients with polycystic ovary syndrome (PCOS). Trace elements and its correlation with insulin resistance are well documented. Aim of Study: The current study aimed to determine possible correlations between insulin resistance and some trace elements (molybdenum, manganese, selenium and chromium) in patients with PCOS. Study Design: Case-control study. The study was performed in the infertility clinic at Babylon hospital for children and maternity. The duration of this study was from October 2014 to December 2015. Methodology: The study involved sixty women (thirty women had PCOS and thirty women were controls). Aspectrophotometrically procedure was used to analyze trace elements (molybdenum, manganese, selenium and chromium) in the serum. In addition the blood glucose and serum insulin during fasting were measured and insulin resistance (IR) was determined using the homeostasis model assessment (HOMA). Results: Body mass index (BMI) in patients with PCOS was increased compared to controls. HOMA and fasting serum insulin were significantly higher in women with PCOS in comparison with controls. There was no difference in blood glucose in women with polycystic ovary in comparison with controls. The cohort was divided into insulin sensitive (NIR) and insulin resistant (IR) patients with PCOS. Women with PCOS-IR had significantly lower serum chromium, selenium and molybdenum and higher serum manganese than women with PCOS-NIR (p-value <0.05). Conclusion: There was a correlation between the levels of serum chromium, selenium, molybdenum and manganese and IR in patients with PCOS.
Authors and Affiliations
Milal M. Al-Jeborry
Keywords
Related Articles
- EP ID EP311541
- DOI 10.9734/BJMMR/2017/31503
- Views 67
- Downloads 0
Plasma N-terminal Pro Brain Natriuretic Peptide as a Prognostic Biomarker in Children with Pulmonary Hypertension
Aim: To evaluate plasma level of N-terminal pro brain natriuretic peptide (NT pro-BNP) as a prognostic biomarker in children with pulmonary hypertension (PH) due to congenital heart disease (CHD). Study Design: Prospecti...
Important Signs in Musculoskeletal MRI
The purpose of this article is to review the common MRI signs of musculoskeletal pathology. In this article, 15 classic MRI signs used in musculoskeletal radiology are presented and described. These signs include the ant...
The Role of Indirect Immunofluorescence Methods in the Detection of Autoimmune Antibodies in Thyroid Disease
Aims: In this study, we evaluated the prevalence of antithyroglobulin antibodies (anti-Tg Ab) and antipyroxidase antibodies (anti-TPO Ab) in thyroid disease and investigated the role of indirect immunofluorescence method...
Static Magnetic Field Effect on Cardiovascular Regulation: A Review
Mounting evidence suggests that environmental and occupational magnetic fields affect cardiovascular system. In this review, supported by original hemodynamic recordings - direct experimental evidence of the effect - sta...
Accuracy of Blood Loss Determination after Vaginal Delivery: Visual Estimation versus Calibrated Measurement
Background: The ability to determine accurately, the blood loss during childbirth is of extreme importance in the diagnosis and management of primary postpartum haemorrhage (PPH). Aims: In this study, we evaluate the eff...