Spectrophotometric Estimation of Zolpidem in Tablets
Journal Title: Journal of Pharmaceutical Sciences and Research - Year 2010, Vol 2, Issue 1
Abstract
A simple, sensitive, rapid, accurate and precise spectrophotometric method has been developed for the estimation of Zolpidem tartrate in bulk and pharmaceutical dosage forms. Zolpidem tartrate shows maximum absorbance at 238.5 nm with molar absorptivity of 4.4648×104lit/mol/cm. Beer’s law was obeyed in the concentration range of 2-16 μg/ml. The limit of detection and limit of quantification were found to be 0.038152 μg/ml and 0.114577 μg/ml, respectively. Results of analysis were validated statistically and by recovery studies.
Authors and Affiliations
K. S. Patil , Y. V. Pore , S. B. Bhise
Keywords
Related Articles
- EP ID EP118746
- DOI -
- Views 104
- Downloads 0
Polysaccharide gum matrix tablets for oral controlled delivery of Cimetidine
Matrix-based tablets using 40 %w/w grewia gum were prepared by direct compression to contain cimetidine as novel drug. The formulations were compared with similar formulations using hydroxypropyl methylce...
Pharmacological studies of anti-diarrhoeal activity of Guettarda speciosa (L.)in experimental animals.
Aims: The purpose of the present study was to evaluate scientifically the anti-diarrhoeal effects of ethanolic (90%) extract of inner bark of Guettarda speciosa. Linn (EEGS) was studied against castor oil-induced-diarrho...
Production of a thermostable extracellular amylase from thermophilic Bacillus species
Isolation and identification of thermophilic Bacillus sp was carried out from a soil sample. The cells were cultivated in a medium containing soluble starch as sole carbon source. The addition of calcium (10 m...
Pharmacognostic and Preliminary Phytochemical Investigations on the stem of Saccharum spontaneum
The genus “Saccharum” includes about 150 species under the family “Poaceae”. This occurs throughout India along the sides of the river and tropics of old world, it is widely distributed in Andhra Pradesh, Vell...
N-Substituted-3-chloro-2-azetidinones: Synthesis and characterization of new novel anti-inflammatory agents
Various substituted 4-(m-hydroxy-p-methoxy phenyl)-1-[(6'-fluoro-7'-substituted (1,3)-benzothiazol-2'-yl) amido-2- phenyl]-3-chloro azetidin–2–one containing different functional groups have been synthesized by treating...