Spectroscopic characterization and cytotoxic activity of new metal complexes derived from (1E, N'Z, N'Z)-N',N'-bis(2-hydroxybenzylidene)-2-(naphthalen-1-yloxy) acetohydrazonohydrazide.
Journal Title: JOURNAL OF ADVANCES IN CHEMISTRY - Year 2015, Vol 11, Issue 9
Abstract
Spectroscopic (IR, 1H-NMR, UV-visible, mass and ESR spectra) and structural studies of the ligand (1E, N'Z, N'Z)-N', N'-bis (2-hydroxybenzylidene)-2-(naphthalen-1-yloxy) acetohydrazonohydrazide (H2L) and its metal complexes are reported. The magnetic properties and thermal analyses (DTA and TGA) were also carried out. The IR spectra of the prepared complexes suggested that, the ligand adopted either a bidentate or a tetradentate fashion, bonding to the metal ion through the azomethine nitrogens and the two phenolic oxygen atoms (ONNO). Electronic spectra and magnetic susceptibility measurements revealed an octahedral geometry for all complexes except sliver(I) complex (6), copper(II) complex (7) and cobalt(II) complex (11). The elemental analyses and mass spectral data have justified the ML, ML2 and M3L composition of the complexes. The ESR spectra of copper(II) complexes (5), (7), (12) and (16), showed an axial type (dx2-y2) ground state with a covalent bond character and also support the suggested structures of complexes. The antimicrobial activity as well as the cytotoxicity of the ligand and its metal complexes were investigated and discussed.
Authors and Affiliations
Abduo S. El-Tabl, M. M. Abd-El Wahed, M. A. Wahba
Keywords
Related Articles
- EP ID EP652865
- DOI 10.24297/jac.v11i9.2681
- Views 118
- Downloads 0
Electronic Properties and Vibratational Analysis of Synthesized g-C3N4 nanoparticles using Density Functional Theory
In the present work, Polymeric metal free Graphitic carbon nitride (g-C3N4) nano particle was synthesized by thermal pyrolysis method without any additives or surfactants. XRD and SEM micrographs clearly show the formati...
The Spectroscopic and theoretical investigations of complex formation of (3E,3'E)-7,7'-(carbonylbis(azanediyl))bis(3-(2-(2-hydroxyphenyl)hydrazono)-4-oxo-3,4-dihydronaphthalene-2-sulfonic acid) with metal cations
A novel azo-dye was isolated by a diazo-coupling reaction and characterized by the elemental analysis, mass spectra, IR and UV-VIS spectroscopy. The processes of complex formation of H4L with some mono-, bis-, and...
Physicochemical characteristics of shea kernels and kinetics of shea butter press extraction
Morphological study of some non conventional oil seeds are of great interest for the development of some communities. In this investigation, shea kernels from 4 localities in Chad were studied. The sun dried shea kernels...
Removal of Carcinogenic Hexavalent Chromium by Reduction with Iron in Presence of Accelerator Non Toxic Organic Compounds (Chalcone)
The focus of this work is on Cr, which has two predominant oxidation states of the atmosphere: + â€3, which is an essential nutrient in low doses, and +â€6, which is highly toxic and carcinogenic. We found that, the re...
Direct Spectrophotometric Determination of Cefuroxime Axetil in Pure Form and Pharmaceutical Dosage Forms.
A simple, direct and cost-effective spectrophotometric method for determination of cefuroxime axetil (CRXA) in pure and tablet dosage forms was applied. This method is based on formation of ion-pair complex ([CRXA]...