Spectrum of Histopathological Changes of Endometrium in Dysfunctional Uterine Bleeding - A Hospital Based Study
Journal Title: Journal of Medical Science And clinical Research - Year 2015, Vol 3, Issue 5
Abstract
DUB is the most common complaint in gynaecology outpatient department. Histopathological evaluation of endometrial tissue plays a significant role in the diagnosis of DUB. The study was carried out to determine the spectrum of histopathological changes of endometrial tissue in women in the age group of 20 40 years presenting with DUB. Formalin fixed specimens (endometrial curettings and hysterectomy specimens) were examined grossly, processed routinely and sections were stained with H&E stain and microscopic findings were noted. A total of 106 cases were analyzed. Normal cyclical endometrium was seen in 55(52%) cases, followed by abnormal endometrium 48(45%)cases and others(endometritis, product of conception) 3(3%) cases. Of the 55 cases of normal cyclical endometrium, proliferative endometrium was highest with 38(69%) cases, followed by secretory endometrium 13(24%) cases, anovulatory endometrium 4(7%).Out of 48 cases of abnormal endometrium,35 (73%) cases was of endometrial hyperplasia, atropic endometrium 6(13%)cases, endometrial carcinoma 4 (8%) cases and endometrial polyp 3(6%). Histopathological evaluation of endometrial curettage and hysterectomy specimens is specially recommended in patients with dysfunctional uterine bleeding to rule out the possibility of any preneoplastic or neoplastic conditions.
Authors and Affiliations
Dr Aparna Langthasa
Keywords
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