Stephania glabra (Menispermaceae)- Phytochemical Perspective.
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 6
Abstract
Background- Stephania glabra (Roxb) has long been used for the treatment of asthma with several other valuable uses. Over 150 alkaloids together with Flavonoids lignans, steroids, Terpenoids and coumarins have been identified in genus stephania. About 30 types of alkaloids are alone identified in S. glabra out of that Gindarudine and tetrahydropalmitine being the major one. Several other chemical constituents from the plant has been evaluated by using different chromatographic and Spectroscopical methods. Method-In the present study the ethanolic extract from the leaves of Stephania glabra was extracted by soxhlet apparatus. So obtained extract was redissolved in ethanol and evaluated for UV for 1, 0.1 and 0.01 % of after redissolving in ethanol also the FTIR spectroscopy was checked. Result-The UV Wavelength for 1%,0.1% and 0.01% dilutions was recorded between 92.15 and 92. 2 which was considered as 92. Gindarudine was its structural moiety with atropine the constituent used for the treatment of asthma. Again, the ftir data confirms the presence of Gindarudine and Tetrahydropalmitine after interpretion. Conclusion-From the whole study it is concluded that S. glabra can be used to formulate novel drug for the treatment of analgesia, inflammation and arthritis.
Authors and Affiliations
HemRaj Vashist
Keywords
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- EP ID EP422644
- DOI 10.9790/3008-1306023540.
- Views 105
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