Struma Ovarii Associated with Pseudo-Meigs’ Syndrome: A Rare Presentation of an Infrequent Tumor
Journal Title: Middle East Journal of Cancer - Year 2017, Vol 8, Issue 1
Abstract
Struma ovarii is an uncommon highly specialized ovarian teratoma that accounts for less than 5% of mature teratomas. It is composed predominantly of mature thyroid tissue. Thyroid tissue is observed in 5%-15% of teratomas; however, to qualify as a struma ovarii tumor, the thyroid proportion must comprise more than 50% of the overall tissue. The combination of pseudo Meigs'syndrome and elevation of CA 125 with struma ovarii is a rare condition that can mimic ovarian malignancy. The majority of strumas are benign, however occasionally malignant transformation may be seen. We have reported a case of benign struma ovarii that presented with the clinical features of advanced ovarian carcinoma: complex pelvic mass, gross ascites, bilateral pleural effusion, and markedly elevated serum CA 125 levels. The patient underwent total abdominal hysterectomy and bilateral salpingo oophorectomy. Ascites and pleural effusion resolved completely, and the CA 125 levels have returned to normal following surgical excision. Patients with pseudo-Meigs’ syndrome may present a diagnostic problem as they masquerade as carcinoma with malignant effusions. In addition, the coexistence of struma ovarii and pseudo-Meigs’ syndrome is a very rare event. We emphasize by this report that, despite its rarity, a differential diagnosis of struma ovarii should be included for an ovarian mass.
Authors and Affiliations
Sonia Chhabra, Namita Bhutani, Sunita Singh, Mansi Aggarwal, Rajeev Sen
Keywords
Related Articles
- EP ID EP298116
- DOI -
- Views 114
- Downloads 0
The Diagnostic Role of Arginase-1, MOC-31, and CDX2 in the Differentiation of Hepatocellular Carcinoma, Cholangiocarcinoma, and Metastatic Colonic Carcinoma of the Liver
Background: Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Pathologic differentiation between HCC from metastatic carcinoma and cholangiocarcinoma has critical therapeutic implications. However,...
Efficacy of Phenytoin Mucoadhesive Tablet versus Mouthwash on Chemotherapy-Induced Oral Mucositis: A Randomized Clinical Trial
Background: Oral mucositis is one of the painful, debilitating and common complications in the patients under chemotherapy for which no certain and effective treatment has not been considered. The aim of this pilot study...
The Effect of Placenta Growth Factor Knockdown on hsa-miR-22-3p, hsa-let-7b-3p, hsa-miR-451b, and hsa-mir-4290 Expressions in MKN-45- derived Gastric Cancer Stem-like Cells
Background: Placental growth factor is involved in human gastric cancer initiation and progression through stimulating the proliferation, angiogenesis, invasion and metastasis of cancerous cells. Previous studies indicat...
Participation in Daily Life Activities among Children with Cancer
Background: Participation in daily life activities is an essential aspect of health, which can facilitate a child’s development. Children with cancer are at risk of functional limitations and participation restrictions....
Myxofibrosarcoma of the Breast in a Young Pregnant Woman: A Case Report and Review of the Literature
Sarcomas of the breast are rare and comprise less than 1% of mammary cancers. Myxofibrosarcoma as an unusual variant of malignant fibrous histiocytoma in the breast and during pregnancy has not previous been reported in...