STUDIES ON HEAVY METAL TOLERANCE AND ANTIBIOTIC RESISTANCE PATTERNS OF BACTERIAL POPULATION ISOLATED FROM EFFLUENT TREATED WATER OF DELHI
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2013, Vol 2, Issue 5
Abstract
Along with the growing industrialization, problem of toxic heavy metal contamination is increasing worldwide. Microbes related technologies may provide an alternative or addition to conventional method of metal removal or metal recovery. The present study dealt with isolation, identification and characterization of microorganisms showing tolerance towards several heavy metals and resistance against antibiotics. These bacterial strains were isolated from different effluent treatment plants located in suburb of Delhi. Initially samples were analyzed for the presence of B.cereus, P.aeruginosa, E. coli & S.aureus through biochemical and morphological methods. Primary screening methods were applied to isolate heavy metals (viz. lead, zinc and cadmium) resistant organisms. Further susceptibility patterns of these isolates were studied towards clinically significant antibiotics such as meropenem, Doxycycline, streptomycin, tetracycline, gentamycin, cloxacillin, amoxicillin, ampicillin, vancomycin, and cephalosporin. All isolates were found to have 100% susceptibility against cadmium & 100% resistance against lead except P.aeruginosa (67%). Doxycycline was found to be most inert antibiotic as it was ineffective against all isolates, whereas meropenem was found to be most promising antibiotic followed by cephalosporin, streptomycin, tetracycline, and gentamycin. These heavy metal resistant organisms could be a potential agent for bioremediation of heavy metals polluted environment.
Authors and Affiliations
Shraddha Sinha*| Department of Microbiology, Shriram Institute for Industrial Research 19, University road, Delhi.-11007, India, Rudrangshu Chatterjee| Department of Microbiology, Shriram Institute for Industrial Research 19, University road, Delhi.-11007, India, Dushyant Singh| Department of Microbiology, Shriram Institute for Industrial Research 19, University road, Delhi.-11007, India, Amita Gaurav Dimri| Department of Microbiology, Shriram Institute for Industrial Research 19, University road, Delhi.-11007, India, ML Aggarwal| Department of Microbiology, Shriram Institute for Industrial Research 19, University road, Delhi.-11007, India
Keywords
Related Articles
- EP ID EP2294
- DOI -
- Views 365
- Downloads 30
FORMULATION AND EVALUATION OF GLIMEPIRIDE PATCHES FOR TRANSDERMAL DRUG DELIVERY
Transdermal drug delivery has been accepted as a potential non-invasive route of drug administration, with advantages of prolonged therapeutic action, less side effect, easy use and improved patient compliance. Glimepiri...
Evaluating the Antischistosomal Activity of Crude Extracts of Carica Papaya against Schistosoma Mansoni: the Interplay of Cellular and Humoral Immunity
Carica papaya is widely used in different parts of Kenya for the treatment of intestinal helminthes. The present study was designed to evaluate the anti-schistosomal effect of a methanolic and aqueous extract of Carica p...
Validation of Reference Genes for Reliable Gene Expression Study in Human Glioblastoma Multiformeand Neural Stem Cell Lines
Glioblastoma multiforme (GBM) is the most deadly malignant brain tumor in adults. GBM has a histologically heterogeneous group of neoplastic cells which are postulated to be the mediator of anti-cancer therapy resistance...
THE ANTIMICROBIAL EFFECT OF AQUEOUS EXTRACT OF TAMARIND (TAMARINDUS INDICA) LEAVES
This study is comparative-experimental work. It was conducted in National Center for Research (Sudan) during the period from 28th of August to 20th December 2013 to investigate the antimicrobial activity of aqueous extra...
HEALTH CLAIM REGULATIONS FOR DIETARY SUPPLEMENTS IN US
Dietary supplements in the recent years have witnessed a tremendous increase in the interest among the consumers due to their potential of providing health benefits. These foods are being marketed globally especially i...