STUDIES ON MICROWAVE ASSISTED SYNTHESIS OF SOME SCHIFF BASES
Journal Title: International Research Journal of Pharmacy (IRJP) - Year 2013, Vol 4, Issue 11
Abstract
The microwave assisted organic synthesis is becoming very popular in recent years owing to its merits over the conventional methods. Some reactions in which conventional heat do not promote are facilitated by microwave irradiation. It is economical, environmentally benign and rapid. We have exploited microwaves for synthesis of some Schiff bases (1a to 1h) by condensing various substituted aromatic aldehydes with hydrazone, obtained by reacting 2-acetyl naphthalene with hydrazine hydrate in the presence of glacial acetic acid. A considerable increase in the reaction rate has been observed with better yield in microwave technique compared to the conventional method. The structures of all the synthesized compounds have been characterized on the basis of Physical constants (m.p, Rf value) and Spectral data {IR (KBr, cm-1), 1HNMR (δppm)}.
Authors and Affiliations
Enamul S Hassain , Chaluvaraju KC, Niranjan MS, Zaranappa , Santhosh C
Keywords
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- EP ID EP157229
- DOI 10.7897/2230-8407.041122
- Views 120
- Downloads 0
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