Study of changes in clinical symptoms and some biologic parameters in asthma patients allergic to D.pteronyssinus treated by sublingual and subcutaneous immunotherapy
Journal Title: JOURNAL OF FUNCTIONAL VENTILATION AND PULMONOLOGY - Year 2018, Vol 9, Issue 28
Abstract
Introduction. Although subcutaneous immunotherapy (SCIT) is traditional method for allergic asthma treatment, it has disadvantages that are the reasons why patients refuse the treatment. However, Sublingual immunotherapy (SLIT) seems to be safe and easy to use. Objective. to evaluate the changes of clinics and immunologic parameters in allergic asthma patients to Dermatophagoides pteronyssinus (Dp) treated by SLIT and SCIT before and after 6 months of treatment. Method. All patients diagnosis specific allergic asthma to Dp were divided into 2 groups: group 1 including 30 patients treated with SLIT and group 2: 30 patients treated with SCIT. This is a blind placebo study method at Haiphong Medical University Hospital. Results. Clinical symptoms decreased significantly (p<0.01) in both groups. Total IgG increased in both groups. Total IgE, destroying mastocyte decreased (p<0.01) in both groups. However, No difference can be found in clinical and immunological changes in allergic asthma patients treated by SLIT compared with SCIT (p>0.05). Conclusions. SLIT and SCIT were clinically effective and safe in allergic asthma to Dp treatment. But SLIT seems to be safe and easy to use more than SCIT.
Authors and Affiliations
Thuc PHAM VAN
Keywords
Related Articles
- EP ID EP570342
- DOI 10.12699/jfvpulm.9.28.2018.53
- Views 63
- Downloads 0
Study on the impact of CO2 inflation on cardiorespiratory system in patients having endoscopy surgery
Objective. To describe the change of heart rate (HR), respiratory rate, and blood pressure in patients with abdominal endoscopic anesthesia surgery when CO2 pumps into peritoneal cavity. Methods. It was a perspective an...
Multidisciplinary management of massive pulmonary embolism on term pregnancy: the mother or the baby?
Introduction. Pulmonary embolism (PE) during pregnancy is the leading cause of maternal and fetal deaths. We report the case of a pregnant patient who has been successfully treated for massive pulmonary embolism associat...
Study of changes in clinical symptoms and some biologic parameters in asthma patients allergic to D.pteronyssinus treated by sublingual and subcutaneous immunotherapy
Introduction. Although subcutaneous immunotherapy (SCIT) is traditional method for allergic asthma treatment, it has disadvantages that are the reasons why patients refuse the treatment. However, Sublingual immunotherapy...
The real conditions and the number of factors related to asthmatic patients in Quoc Tuan commune - An Lao district and Hong Thai commune - An Duong district in Hai Phong city - Vietnam
We conducted a cross-sectional survey in August 2013 on the status of bronchial asthma in Quoc Tuan community in An Lao district, Hong Thai commune, An Duong district, Hai Phong. By the total sampling method, the study c...
Allergic rhinitis, upper airway and quality of sleep
The symptoms of allergic rhinitis (AR) include rhinorrhea, nasal pruritus and sneezing, and nasal congestion. AR is usually associated with the allergic symptoms of another organs such as the eyes and throat. Nasal conge...