Study of changes in the clinics, lung function and skin prick-test in asthmatic patients allergic to D.pteronyssinus under the effect of sublingual immunotherapy
Journal Title: JOURNAL OF FUNCTIONAL VENTILATION AND PULMONOLOGY - Year 2018, Vol 9, Issue 28
Abstract
Introduction. First step in evaluation of the efficacy of allergic asthma to Dermatophagoides pteronyssinus (Dp) by using sublingual immunotherapy (SLIT) through the change of clinics, prick test, and lung ventilation is very necessary to confirm its validity. Objective. To study the change of clinics, lung ventilation, prick test and the efficacy of SLIT in asthma to Dp treatment. Method. Auto controlled follow-up study included 30 patients with allergic asthma to Dp at Haiphong Medical University Hospital. This is descriptive study method and all patients were selected by convenient sampling. Results. After treatment, cough reduced from 80% to 26.67%; the number of outbreak ≥ 3 times/month from 60% to 6.67%; wheezing and sonorous rales from 86.67% to 23.34%. FEV1: before treatment 78,12±11.2 and after 92.04±16.02; PEF: before treatment 84.1±11.6 and after 91.08±14.9. Prick test: before treatments 100% were positive and after 26.67% negative. Common efficacy of therapy: Excellent, good were 70%, average 23.33%, and bad 6.67%. Conclusion. SLIT is good in allergic asthma to Dp treatment.
Authors and Affiliations
Thuc PHAM VAN
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