Study of Clinical Profile And Lab Parameters Of Vivax And Falciparum Malaria In Children: Data From A Northern Rural Centre
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 8
Abstract
Background: Malaria is one of the most widespread infectious diseases in humans. Plasmodium falciparum and plasmodium vivax cause the maximum morbidity and mortality. The present study was done prospectively, to note the clinical profile and lab parameters in children infected with P. falciparum. Methods: A total of 100 pediatric patients with confirmed malarial infection (falciparum or vivax) and under the age of 18 years were enrolled. All the patients were well examined with a detailed history and all necessary hematological and biochemical investigations done were noted. Data was compiled and compared between both forms of malarial infections. Results: Out of 100 patients enrolled with positive rapid diagnostic tests for malaria, 85% were positive for plasmodium vivax, 13% for plasmodium falciparum and 2% for mixed infection with both these species. The age ranged from 0-18 years with M:F ratio of 1.94 : 1. The most common symptom noted was fever (98%) and finding present on examination was pallor (56%). Splenomegaly was found in 42% while bot hepatomegaly and splenomegaly was present in 20% of cases. Lab investigations revealed statistically significant difference (p= 0.03 & 0.005) of deranged renal function tests (S. urea and creatinine) in P. falciparum (50% and 66.7%) as compared to P. vivax (50% and 33.3%). None other lab parameters had significant difference between the two species of infection. Conclusion: Our study highlights that the plasmodium vivax is a commoner form of malarial infection in children but the risks and deranged renal functions are more seen in falciparum malaria which is finally responsible for higher morbidity and mortality.
Authors and Affiliations
Gauri Chauhan
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