Study of dyslipidemia in Type 2 Diabetes Mellitus and its correlation with glycemic parameters
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 3
Abstract
Introduction: Diabetes Mellitus (DM), caused by relative or definite insulin deficiency or by insulin resistance is a progressive chronic disease leading to hyperglycemia, characterized by disorders of carbohydrate, lipid and protein metabolism. Dyslipidemia is a well-known factor leading to atherosclerosis. Diagnosis and treatment of dyslipidemia in patients with diabetes is important in reducing the high morbidity and mortality from macrovascular disease. Thus we designed a study to assess the prevalence and pattern of dyslipidemia in type 2 DM, and also to determine its association with biochemical markers of diabetes mellitus. Materials & Methods: This was a non-interventional and observational study. We included 100 T2DM patients (50 males & 50 females) in our study. Convenient sampling technique was used for the present study. The patients and their legally acceptable representative were given complete information about the study, its benefits, and its future prospects. Patient’s detailed physical and clinical examination, history was taken. Each of the subjects were evaluated for body weight, height, BMI and for WC. Results: 43 (43%) patients had optimal LDL cholesterol level, 29 (29%) patients had near optimal/above optimal LDL cholesterol level, 25 (25%) patients had borderline high LDL cholesterol level, 2 (2%) patients had high LDL cholesterol level and 1 (1%) patient had very high LDL cholesterol level. 28 (28%) patients in our study were having deranged LDL cholesterol level (>130 mg/dl). 65 (65%) patients had total cholesterol level in the desirable range, 28 (28%) patients had borderline high total cholesterol level and 7 (7%) patients had high total cholesterol level. 35 (35%) patients in our study were having deranged total cholesterol (> 200 mg/dl). In our study we found negative but statistically non-significant correlation of HbA1c and PPBS with HDL cholesterol. Conclusion On the basis of our study we conclude that dyslipidemia in diabetes mellitus is very common and it is associated with poor glycemic control. Thus, we recommend routine estimation of lipid profile along with strict glycemic control and healthy life style modification among the patients with T2DM.
Authors and Affiliations
Dr. Abhishek Singhai
Keywords
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