STUDY OF FEW TETRALONE DERIVATIVES
Journal Title: Mintage journal of pharmaceutical and medical sciences - Year 2016, Vol 5, Issue 4
Abstract
Tetralone ring system has drawn an immense attention in the field of drug discovery by virtue of their wide applications as an analgesic, antidepressant, antifungal and antibacterial. The wide range of its therapeutic application paved the way to the researchers to introduce this nucleus frequently in the diversified molecular skeleton to generate novel compounds with high therapeutic value. In this case, we have tried to present various therapeutic applications, which have already been demystified by the researchers. The study may prompt the researcher to generate scaffolds of highest therapeutic efficacy considering the importance of tetralone nucleus. All the synthesized products were characterized by spectral and elemental analysis data.
Authors and Affiliations
sourav de, subhasis banerjee, c. navya keerthi, b. mohana lakshmi
Keywords
Related Articles
- EP ID EP438960
- DOI -
- Views 117
- Downloads 0
ANTIMICROBIAL ACTIVITY OF VARIOUS EXTRACTS OF THE SPIRULINA PLATENSIS AGAINST VIBRIO FLUVIALIS
The aim of the present study was to evaluate antibacterial activity of the crude extracts of Spirulina platensis against a marine pathogen. Crude algal extracts were prepared in water, ethanol and acetone with different...
WATER MEDIATED DIELS-ALDER [4+2] CYCLOADDITION REACTION: A GREEN CHEMICAL APPROACH FOR THE SYNTHESIS OF SOME 2-(6-METHOXY-2-NAPHTHYL)-3-(SUBSTITUTED PHENYL) BICYCLO [2.2.1] HEPTA-5-ENE-2-ONES AND EVALUATION OF BIOLOGICAL ACTIVITIES
Objective: To synthesis some 2-(6-methoxy-2-naphthyl)-3-(substituted phenyl) bicyclo[2.2.1] hepta-5-ene ketones and evaluation of their biological activities. Methods: Green chemical approach of water mediated fly-ash...
LATERAL MEDULLARY SYNDROME (WALLENBERG SYNDROME) AND DYSPHAGIA – A CASE REPORT
Lateral Medullary Syndrome (LMS) or Wallenberg Syndrome or Posterior Inferior Cerebellar Artery (PICA) Syndrome is a rare prevailing cause of stroke. Varied presentations of LMS such as distortion of speech, orientation...
FORMULATION AND EVALUATION OF SOLID DISPERSION CONTAINING ASPIRIN
Objective: The objective of the study is to increase the solubility by solid dispersion method and to compare dissolution of pure drug and solid dispersions.Aspirin (Acetyl Salicylic Acid)is poorly soluble in water show...
A STUDY ON THE LUNAR PERIODICITY OF INSECT ABUNDANCE USING LIGHT TRAP
The present study aimed to understand the lunar periodicity of insect abundance using light trap. It mainly involves handpicking of insects that are coming under light for a period of one month. The collected insects are...